Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.
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Identification of a human follicular dendritic cell molecule that stimulates germinal center B cell growthIllegitimate WNT signaling promotes proliferation of multiple myeloma cellsCD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferationStructures of the alpha L I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation.Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistanceDOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memoryStromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodesB-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1CD9 may contribute to the survival of human germinal center B cells by facilitating the interaction with follicular dendritic cells.Integrin-mediated interactions between B cells and follicular dendritic cells influence germinal center B cell fitnessThe pathophysiologic role of alpha 4 integrins in vivoCross-linking of CD80 and CD86 Diminishes Expression of CD54 on EBV-transformed B Cells through Inactivation of RhoA and RasSpecialized functional properties of the integrin alpha 4 cytoplasmic domain.Apoptosis and interleukin 7 gene expression in chronic B-lymphocytic leukemia cells.Estrogen alters thresholds for B cell apoptosis and activationModels of signal transduction through the B-cell antigen receptor.Integrin α4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma.CD49d expression is an independent predictor of overall survival in patients with chronic lymphocytic leukaemia: a prognostic parameter with therapeutic potentialThe Emu-bcl-2 transgene enhances antigen-induced germinal center formation in both BALB/c and SJL mice but causes age-dependent germinal center hyperplasia only in the lymphoma-prone SJL strainProgenitor tumours from Emu-bcl-2-myc transgenic mice have lymphomyeloid differentiation potential and reveal developmental differences in cell survivalHypogammaglobulinemia in newly diagnosed chronic lymphocytic leukemia: Natural history, clinical correlates, and outcomes.How do follicular dendritic cells interact intimately with B cells in the germinal centre?P2Y2 nucleotide receptor activation up-regulates vascular cell adhesion molecule-1 [corrected] expression and enhances lymphocyte adherence to a human submandibular gland cell line.Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.Therapeutic anti-integrin (alpha4 and alphaL) monoclonal antibodies: two-edged swords?Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice.Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrowNeonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune responseImproved monitoring of clinical response in Systemic Lupus Erythematosus by longitudinal trend in soluble vascular cell adhesion molecule-1.Anti-LFA-1 antibodies enhance metastasis of ocular lymphoma to the brain and contralateral eye.Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and functionHAX1 deletion impairs BCR internalization and leads to delayed BCR-mediated apoptosis.Lymphotoxin α1β2 expression on B cells is required for follicular dendritic cell activation during the germinal center responseChanges to anti-JCV antibody levels in a Swedish national MS cohortDifferential expression of IRF8 in subsets of macrophages and dendritic cells and effects of IRF8 deficiency on splenic B cell and macrophage compartments.Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma.Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance.Predominant role of alpha 4-integrins for distinct steps of lymphoma metastasis.Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes.Alpha6-integrin is expressed on germinal centre B cells and modifies growth of a B-cell line.
P2860
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P2860
Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Adhesion through the LFA-1 (CD ...... is of germinal center B cells.
@en
Adhesion through the LFA-1
@nl
type
label
Adhesion through the LFA-1 (CD ...... is of germinal center B cells.
@en
Adhesion through the LFA-1
@nl
prefLabel
Adhesion through the LFA-1 (CD ...... is of germinal center B cells.
@en
Adhesion through the LFA-1
@nl
P2093
P1476
Adhesion through the LFA-1 (CD ...... sis of germinal center B cells
@en
P2093
Keehnen RM
Lindhout E
de Groot C
van Seventer GA
P304
P407
P577
1994-04-01T00:00:00Z