Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2.
about
Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studiesA Genetic-Pathophysiological Framework for CraniosynostosisAngiogenesis and intramembranous osteogenesisHomodimerization Controls the Fibroblast Growth Factor 9 Subfamily's Receptor Binding and Heparan Sulfate-Dependent Diffusion in the Extracellular MatrixEarly onset of craniosynostosis in an Apert mouse model reveals critical features of this pathologyFGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesisDeficiency of zebrafish fgf20a results in aberrant skull remodeling that mimics both human cranial disease and evolutionarily important fish skull morphologiesA mathematical model for mechanotransduction at the early steps of suture formationDerivation of the mammalian skull vaultActivation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.De novo alu-element insertions in FGFR2 identify a distinct pathological basis for Apert syndromeA splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes.A computational analysis of bone formation in the cranial vault in the mouseComparative study on the cellular activities of osteoblast-like cells and new bone formation of anorganic bone mineral coated with tetra-cell adhesion molecules and synthetic cell binding peptideDecreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders.Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome.Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.OSTEOPONTIN: A KEY LINK BETWEEN IMMUNITY, INFLAMMATION AND THE CENTRAL NERVOUS SYSTEM.Further analysis of the Crouzon mouse: effects of the FGFR2(C342Y) mutation are cranial bone-dependentAugmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice.Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.Understanding craniosynostosis as a growth disorderFGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion.Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.Hand in glove: brain and skull in development and dysmorphogenesis.Calvarial Defects: Cell-Based Reconstructive Strategies in the Murine Model.Signaling networks in joint development.BCL11B regulates sutural patency in the mouse craniofacial skeleton.A model for the pharmacological treatment of crouzon syndrome.Twist is required for establishment of the mouse coronal suture.Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation.Mechanism of skull suture maintenance and interdigitation.Postnatal development of lymphatic vasculature in the brain meninges.Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant.
P2860
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P2860
Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@en
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@nl
type
label
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@en
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@nl
prefLabel
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@en
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@nl
P2093
P1433
P1476
Fgfr2 and osteopontin domains ...... tered by locally applied FGF2.
@en
P2093
P304
P407
P577
1997-09-01T00:00:00Z