Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.
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Structural basis for fibroblast growth factor receptor 2 activation in Apert syndromeCbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiationIntracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278FFibroblast growth factor signaling in skeletal development and diseaseThe roles of fibroblast growth factors in the testicular development and tumorCloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitroThe role of Axin2 in calvarial morphogenesis and craniosynostosisExpression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast DifferentiationOverexpression of Nell-1, a craniosynostosis-associated gene, induces apoptosis in osteoblasts during craniofacial developmentEarly onset of craniosynostosis in an Apert mouse model reveals critical features of this pathologyFGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesisConcerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone developmentSox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiationSystematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts.β1A integrin is a master regulator of invadosome organization and function.Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition.Combination of Bioactive Polymeric Membranes and Stem Cells for Periodontal Regeneration: In Vitro and In Vivo Analyses.The effect of combination of recombinant human bone morphogenetic protein-2 and basic fibroblast growth factor or insulin-like growth factor-I on dental implant osseointegration by confocal laser scanning microscopy.Defective osteoblast function in ICAP-1-deficient miceDifferential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bonesLysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts.Activation of FGF signaling mediates proliferative and osteogenic differences between neural crest derived frontal and mesoderm parietal derived bone.Development of a unique system for spatiotemporal and lineage-specific gene expression in mice.A common variant in fibroblast growth factor binding protein 1 (FGFBP1) is associated with bone mineral density and influences gene expression in vitroMechanisms balancing skeletal matrix synthesis and degradation.The BMP antagonist noggin regulates cranial suture fusion.Investigation of FGFR2-IIIC signaling via FGF-2 ligand for advancing GCT stromal cell differentiation.Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cellsEffects of thyroxine exposure on osteogenesis in mouse calvarial pre-osteoblasts.Bone tissue engineering: recent advances and promising therapeutic agents.Synergistic effects of high dietary calcium and exogenous parathyroid hormone in promoting osteoblastic bone formation in mice.Stage-specific effects of fibroblast growth factor 2 on the differentiation of dental pulp cells.Inhibited Wnt signaling causes age-dependent abnormalities in the bone matrix mineralization in the Apert syndrome FGFR2(S252W/+) miceApert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells.A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiation.FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest.The effect of a Beare-Stevenson syndrome Fgfr2 Y394C mutation on early craniofacial bone volume and relative bone mineral density in mice.Effects of growth factors and cytokines on osteoblast differentiation.Drug-sensitive FGFR2 mutations in endometrial carcinomaFurther analysis of the Crouzon mouse: effects of the FGFR2(C342Y) mutation are cranial bone-dependent
P2860
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P2860
Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.
description
2000 nî lūn-bûn
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2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
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2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
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2000年學術文章
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name
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@ast
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@en
type
label
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@ast
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@en
prefLabel
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@ast
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@en
P2860
P356
P1476
Signaling by fibroblast growth ...... uces apoptosis in osteoblasts.
@en
P2093
P2860
P304
P356
10.1083/JCB.149.6.1297
P407
P577
2000-06-01T00:00:00Z