The effect of inhibitor binding on the structural stability and cooperativity of the HIV-1 protease.
about
Structural Analysis of Human Immunodeficiency Virus Type 1 CRF01_AE Protease in Complex with the Substrate p1-p6Exploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein–protein interaction in C. hominis thymidylate synthase-dihydrofolate reductase (TS-DHFR)Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitorThe nature of protein domain evolution: shaping the interaction networkA systematic study of the vibrational free energies of polypeptides in folded and random states.Point mutations and sequence variability in proteins: redistributions of preexisting populations.Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis.Folding and binding cascades: dynamic landscapes and population shifts.Effects of HIV-1 protease on cellular functions and their potential applications in antiretroviral therapy.The propagation of binding interactions to remote sites in proteins: analysis of the binding of the monoclonal antibody D1.3 to lysozymeInteraction of I50V mutant and I50L/A71V double mutant HIV-protease with inhibitor TMC114 (darunavir): molecular dynamics simulation and binding free energy studies.Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes.Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathwayA solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex.SiteLight: binding-site prediction using phage display libraries.Overcoming drug resistance in HIV-1 chemotherapy: the binding thermodynamics of Amprenavir and TMC-126 to wild-type and drug-resistant mutants of the HIV-1 proteaseAssociation energetics of cross-reactive and specific antibodiesAnalysis and characterization of dimerization inhibition of a multi-drug-resistant human immunodeficiency virus type 1 protease using a novel size-exclusion chromatographic approachThe effect of prime-site occupancy on the hepatitis C virus NS3 protease structure.Different roles of electrostatics in heat and in cold: adaptation by citrate synthase.Monte Carlo simulations of the peptide recognition at the consensus binding site of the constant fragment of human immunoglobulin G: the energy landscape analysis of a hot spot at the intermolecular interface.
P2860
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P2860
The effect of inhibitor binding on the structural stability and cooperativity of the HIV-1 protease.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@en
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@nl
type
label
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@en
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@nl
prefLabel
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@en
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@nl
P2860
P1433
P1476
The effect of inhibitor bindin ...... ativity of the HIV-1 protease.
@en
P2093
P2860
P304
P356
10.1002/(SICI)1097-0134(19990801)36:2<147::AID-PROT2>3.0.CO;2-3
P407
P577
1999-08-01T00:00:00Z