Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathway
about
The impact of human hyperekplexia mutations on glycine receptor structure and functionPresynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.A novel syndrome of lethal familial hyperekplexia associated with brain malformation.Dynamic multiprotein assemblies shape the spatial structure of cell signalingDistinct properties of glycine receptor β+/α- interface: unambiguously characterizing heteromeric interface reconstituted in homomeric proteinAllosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways.Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activationThe spatial structure of cell signaling systems.Integration of structural dynamics and molecular evolution via protein interaction networks: a new era in genomic medicine.
P2860
Q26830661-011BD684-0F6A-4A1E-BF79-FC8DE6C6E312Q30419923-3CB0939A-2424-49CC-A750-858E5847458BQ30527899-4D75FA1B-68CB-41FB-B08A-903F59BFDFE5Q34602367-0141DF0D-7456-4B14-A590-44888CE265BFQ36033235-D270D5D7-7673-4BE1-9571-88FEA7D15A87Q36147266-715EBA99-A66C-433D-98F2-88EFFF2F2EB6Q37334375-73B30111-71DE-4FEA-BC17-10275B5F1FE6Q37408300-B96B5D48-4B6D-4925-928C-6C54CC1E77E4Q38673851-52BF26F2-3915-475C-A87C-8DAB81D17CF8
P2860
Function of hyperekplexia-causing α1R271Q/L glycine receptors is restored by shifting the affected residue out of the allosteric signalling pathway
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
@zh-cn
name
Function of hyperekplexia-caus ...... allosteric signalling pathway
@ast
Function of hyperekplexia-caus ...... allosteric signalling pathway
@en
type
label
Function of hyperekplexia-caus ...... allosteric signalling pathway
@ast
Function of hyperekplexia-caus ...... allosteric signalling pathway
@en
prefLabel
Function of hyperekplexia-caus ...... allosteric signalling pathway
@ast
Function of hyperekplexia-caus ...... allosteric signalling pathway
@en
P2093
P2860
P1476
Function of hyperekplexia-caus ...... allosteric signalling pathway
@en
P2093
Joseph W Lynch
Qiang Shan
P2860
P304
P356
10.1111/J.1476-5381.2011.01701.X
P407
P577
2012-04-01T00:00:00Z