about
Comprehensive analysis of blood group antigen binding to classical and El Tor cholera toxin B-pentamers by NMR.Thermodynamically-Weighted Conformational Ensemble of Cyclic RGD Peptidomimetics from NOE Data.Potent integrin antagonists from a small library of RGD-including cyclic pseudopeptides.Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids.Biological and molecular properties of a new alpha(v)beta3/alpha(v)beta5 integrin antagonist.A potent integrin antagonist from a small library of cyclic RGD pentapeptide mimics including benzyl-substituted azabicycloalkane amino acids.Insights into the Binding of Cyclic RGD Peptidomimetics to α5β1 Integrin by using Live-Cell NMR And Computational Studies.Insight to the binding mode of triazole RGD-peptidomimetics to integrin-rich cancer cells by NMR and molecular modeling.Determination of the binding epitope of RGD-peptidomimetics to αvβ3 and α(IIb)β3 integrin-rich intact cells by NMR and computational studies.Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.STD and trNOESY NMR study of receptor-ligand interactions in living cancer cells.Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy.Solution Behavior of Amphiphilic Glycodendrimers with a Rod-Like Core.Cyclic RGD-peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.Cyclic isoDGR peptidomimetics as low-nanomolar αvβ3 integrin ligands.Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma.Mimics of ganglioside GM1 as cholera toxin ligands: replacement of the GalNAc residue.Ganglioside GM1 mimics: lipophilic substituents improve affinity for cholera toxin.Cyclic DGR-peptidomimetic containing a bicyclic reverse turn inducer as a selective alpha(v)beta (5) integrin ligand.Cyclic RGD-containing functionalized azabicycloalkane peptides as potent integrin antagonists for tumor targeting.Synthesis of novel DC-SIGN ligands with an alpha-fucosylamide anchor.A NMR and computational study of Smac mimics targeting both the BIR2 and BIR3 domains in XIAP protein.Transferred-NOE NMR experiments on intact human platelets: receptor-bound conformation of RGD-peptide mimics.Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: SynthesisCyclic RGD Peptidomimetics Containing Bifunctional Diketopiperazine Scaffolds as New Potent Integrin LigandsConformational Studies of Chiral Vinylogous SulfonamidopeptidesSynthesis of Sulfonamido-Pseudopeptides: New Chiral Unnatural OligomersStereoselective conjugate addition of lithium and titanium enolates to γ - alkoxy enonesChemical composition and volatile constituents ofAnthyllis barba-jovisCicloastragenol glycosides from astragalus verrucosusSynthesis, Conformational Studies and Mannosidase Stability of a Mimic of 1,2-MannobiosideA new isoflavone from Genista corsicaSecond-generation mimics of ganglioside GM1 oligosaccharide: a three-dimensional view of their interactions with bacterial enterotoxins by NMR and computational methods
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P50
description
hulumtuese
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onderzoeker
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հետազոտող
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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Donatella Potenza
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P106
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7003980496
P21
P31
P496
0000-0001-5469-8027