LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.
about
LRP-1: a checkpoint for the extracellular matrix proteolysisA novel, specific pro-urokinase complex on monocyte-like cells, detected by transglutaminase-catalyzed cross-linkingNormal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1Recycling of the urokinase receptor upon internalization of the uPA:serpin complexesMutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal developmentEndocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration.Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout miceInducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants39 kDa receptor-associated protein is an ER resident protein and molecular chaperone for LDL receptor-related proteinApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyDirect binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activityAmyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophagesLow Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell FunctionApolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer diseaseVEGF-initiated angiogenesis and the uPA/uPAR systemEndothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrierAdenovirus Binding to Blood Factors Results in Liver Cell Infection and HepatotoxicityNMR solution structure of complement-like repeat CR3 from the low density lipoprotein receptor-related protein. Evidence for specific binding to the receptor binding domain of human alpha(2)-macroglobulinCollagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalizationThe urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motilitySoluble low density lipoprotein receptor-related protein (LRP) circulates in human plasmaThe urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingLow-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain developmentVitamin D activation of functionally distinct regulatory miRNAs in primary human osteoblastsFunctional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivoThe very low density lipoprotein receptor mediates the cellular catabolism of lipoprotein lipase and urokinase-plasminogen activator inhibitor type I complexesAnalysis of a two-domain binding site for the urokinase-type plasminogen activator-plasminogen activator inhibitor-1 complex in low-density-lipoprotein-receptor-related proteinContribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and AutoimmunityMapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90Norrin attenuates protease-mediated death of transformed retinal ganglion cellsInflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophagesExtensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's diseaseWhole exome sequencing identifies LRP1 as a pathogenic gene in autosomal recessive keratosis pilaris atrophicansLRP: a multifunctional scavenger and signaling receptorHuman rhinovirus type 2 is internalized by clathrin-mediated endocytosisThe very low density lipoprotein receptor regulates urokinase receptor catabolism and breast cancer cell motility in vitro.Regulation of Rac1 activation by the low density lipoprotein receptor-related proteinLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemMyeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumors
P2860
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P2860
LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
LDL receptor-related protein i ...... ntial for embryo implantation.
@en
LDL receptor-related protein i ...... ntial for embryo implantation.
@nl
type
label
LDL receptor-related protein i ...... ntial for embryo implantation.
@en
LDL receptor-related protein i ...... ntial for embryo implantation.
@nl
prefLabel
LDL receptor-related protein i ...... ntial for embryo implantation.
@en
LDL receptor-related protein i ...... ntial for embryo implantation.
@nl
P2093
P1433
P1476
LDL receptor-related protein i ...... ntial for embryo implantation.
@en
P2093
P304
P356
10.1016/0092-8674(92)90511-A
P407
P577
1992-10-01T00:00:00Z