Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
about
Mutations of a novel human RAD54 homologue, RAD54B, in primary cancerDisruption of maternal DNA repair increases sperm-derived chromosomal aberrationsThe RAD51 family member, RAD51L3, is a DNA-stimulated ATPase that forms a complex with XRCC2The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cellsDifferential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosisDisruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethalityDifferential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell lineHuman Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.A role for RAD54B in homologous recombination in human cellsInteraction of human recombination proteins Rad51 and Rad54Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeThe Rad51 paralog Rad51B promotes homologous recombinational repairDisruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin CFunctional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stressXRCC3 promotes homology-directed repair of DNA damage in mammalian cellsHomologous recombination in DNA repair and DNA damage toleranceDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningComplex formation by the human RAD51C and XRCC3 recombination repair proteinsEme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cellsStimulation of Dmc1-mediated DNA strand exchange by the human Rad54B proteinHomologous Recombination and Its Role in CarcinogenesisDifferences in the DNA replication of unicellular eukaryotes and metazoans: known unknownsYeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA double helix conformation.The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance.Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1.Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Homologous recombination and human health: the roles of BRCA1, BRCA2, and associated proteinsA novel human rad54 homologue, Rad54B, associates with Rad51Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombinationMutations in the RAD54 recombination gene in primary cancersRegulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylationSpatial organization of the mammalian genome surveillance machinery in response to DNA strand breaksMouse models of Fanconi anemiaCellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insightsERCC1-XPF endonuclease facilitates DNA double-strand break repairRad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stabilityHypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient miceDisruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) backgroundConditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells
P2860
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P2860
Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Disruption of mouse RAD54 redu ...... and homologous recombination.
@en
Disruption of mouse RAD54 redu ...... and homologous recombination.
@nl
type
label
Disruption of mouse RAD54 redu ...... and homologous recombination.
@en
Disruption of mouse RAD54 redu ...... and homologous recombination.
@nl
prefLabel
Disruption of mouse RAD54 redu ...... and homologous recombination.
@en
Disruption of mouse RAD54 redu ...... and homologous recombination.
@nl
P2093
P1433
P1476
Disruption of mouse RAD54 redu ...... and homologous recombination.
@en
P2093
Hendriks RW
Hoeijmakers JH
Swagemakers SM
Troelstra C
P304
P356
10.1016/S0092-8674(00)80199-3
P407
P577
1997-04-01T00:00:00Z