Ion-channel gating mechanisms: model identification and parameter estimation from single channel recordings.
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Hidden Markov modeling for single channel kinetics with filtering and correlated noiseA quantitative description of KcsA gating II: single-channel currentsHidden-Markov methods for the analysis of single-molecule actomyosin displacement data: the variance-Hidden-Markov methodInositol trisphosphate receptor and ion channel models based on single-channel data.Two-dimensional components and hidden dependencies provide insight into ion channel gating mechanisms.Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events.Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of alpha-subunit tyrosine 190 affect both binding and gating.Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulationGlutamate receptor-channel gating. Maximum likelihood analysis of gigaohm seal recordings from locust muscle.Efficient maximum likelihood estimation of kinetic rate constants from macroscopic currentsEstimating kinetic parameters for single channels with simulation. A general method that resolves the missed event problem and accounts for noise.Evidence for cooperativity between nicotinic acetylcholine receptors in patch clamp records.The quality of maximum likelihood estimates of ion channel rate constants.Bayesian restoration of ion channel records using hidden Markov models.Use of the covariance matrix in directly fitting kinetic parameters: application to GABAA receptors.Model-based fitting of single-channel dwell-time distributions.Maximum likelihood estimation of ion channel kinetics from macroscopic currentsStatistical evaluation of ion-channel gating models based on distributions of log-likelihood ratios.MCMC estimation of Markov models for ion channels.A promising approach to molecular counting problem in superresolution microscopyAnalyzing single-molecule time series via nonparametric Bayesian inferenceMarkov, fractal, diffusion, and related models of ion channel gating. A comparison with experimental data from two ion channels.Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing.Kinetic structure of large-conductance Ca2+-activated K+ channels suggests that the gating includes transitions through intermediate or secondary states. A mechanism for flickers.Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domainsRyanodine receptor allosteric coupling and the dynamics of calcium sparksComputational Membrane Biophysics: From Ion Channels Interactions with Drugs to Cellular Function.Applying hidden Markov models to the analysis of single ion channel activity.The effects of non-identifiability on testing for detailed balance in aggregated Markov models for ion-channel gating.Ca(2+)- and voltage-dependent gating of Ca(2+)- and ATP-sensitive cationic channels in brain capillary endothelium.Single molecule conformational memory extraction: p5ab RNA hairpin.Activation of recombinant mouse acetylcholine receptors by acetylcholine, carbamylcholine and tetramethylammonium.Gating kinetics of the quisqualate-sensitive glutamate receptor of locust muscle studied using agonist concentration jumps and computer simulationsSingle ion channel models incorporating aggregation and time interval omission.Identifiability, reducibility, and adaptability in allosteric macromoleculesMutation in the M1 domain of the acetylcholine receptor alpha subunit decreases the rate of agonist dissociation.Estimating kinetic mechanisms with prior knowledge I: Linear parameter constraints.Maximum likelihood estimation of aggregated Markov processes.Estimating transition rates in aggregated Markov models of ion channel gating with loops and with nearly equal dwell times.
P2860
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P2860
Ion-channel gating mechanisms: model identification and parameter estimation from single channel recordings.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
@zh-hant
name
Ion-channel gating mechanisms: ...... rom single channel recordings.
@en
Ion-channel gating mechanisms: ...... rom single channel recordings.
@nl
type
label
Ion-channel gating mechanisms: ...... rom single channel recordings.
@en
Ion-channel gating mechanisms: ...... rom single channel recordings.
@nl
prefLabel
Ion-channel gating mechanisms: ...... rom single channel recordings.
@en
Ion-channel gating mechanisms: ...... rom single channel recordings.
@nl
P356
P1476
Ion-channel gating mechanisms: ...... from single channel recordings
@en
P2093
P304
P356
10.1098/RSPB.1989.0029
P577
1989-05-01T00:00:00Z