Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
about
Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowthApolipoprotein C-I binds free fatty acids and reduces their intracellular esterificationStearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscleFatty acid transporters in skin development, function and diseaseA human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl estersIsolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-elementLXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1A plasminogen-like protein selectively degrades stearoyl-CoA desaturase in liver microsomesNormal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glandsAsebia-2J (Scd1(ab2J)): a new allele and a model for scarring alopeciaA toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteriaIdentification of mouse palmitoyl-coenzyme A Delta9-desaturaseEpidermal surface lipids.Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosisGenetic control of de novo lipogenesis: role in diet-induced obesityMetabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism.Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver developmentLoss of stearoyl-CoA desaturase-1 function protects mice against adiposityGenetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans.Cystathionine beta-synthase deficiency causes fat loss in mice.Lipid mediators in acneRole of stearoyl-coenzyme A desaturase in regulating lipid metabolismInsights from the asebia mouse: a molecular sebaceous gland defect leading to cicatricial alopecia.Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables.TGFβ signaling regulates lipogenesis in human sebaceous glands cells.Role of hormones and blood lipids in the pathogenesis of acne vulgaris in non-obese, non-hirsute females.Sebaceous gland, hair shaft, and epidermal barrier abnormalities in keratosis pilaris with and without filaggrin deficiencyThematic review series: skin lipids. Sebaceous gland lipids: friend or foe?Hair follicular expression and function of group X secreted phospholipase A2 in mouse skin.Drosophila Myc: A master regulator of cellular performance.Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity.Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discoveryThe role of fatty acid desaturases in epidermal metabolismGlobal deletion of lipocalin 2 does not reverse high-fat diet-induced obesity resistance in stearoyl-CoA desaturase-1 skin-specific knockout mice.Ulcerative dermatitis in C57BL/6 mice lacking stearoyl CoA desaturase 1.Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome.Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells.Stearoyl-coenzyme A desaturase 1 gene expression increases after pioglitazone treatment and is associated with peroxisomal proliferator-activated receptor-gamma responsiveness.dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth.Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice.
P2860
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P2860
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@en
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@nl
type
label
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@en
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@nl
prefLabel
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@en
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@nl
P2093
P356
P1433
P1476
Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse.
@en
P2093
Eilertsen KJ
Sundberg JP
P2888
P304
P356
10.1038/15446
P407
P577
1999-11-01T00:00:00Z