Decreased DNA repair efficiency by loss or disruption of p53 function preferentially affects removal of cyclobutane pyrimidine dimers from non-transcribed strand and slow repair sites in transcribed strand.
about
Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum CThe relevance of the vitamin D endocrine system (VDES) for tumorigenesis, prevention, and treatment of non-melanoma skin cancer (NMSC): Present concepts and future perspectivesp53 in the DNA-Damage-Repair ProcessSelenomethionine regulation of p53 by a ref1-dependent redox mechanism.Revisiting the rodent repairadox.Animal models of melanoma: an HGF/SF transgenic mouse model may facilitate experimental access to UV initiating events.Measuring the formation and repair of UV damage at the DNA sequence level by ligation-mediated PCRNavigating the nucleotide excision repair threshold.p53 C-terminal interaction with DNA ends and gaps has opposing effect on specific DNA binding by the core.17 beta-Oestradiol attenuates nucleotide excision repair.Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells.Oncogenic H-Ras enhances DNA repair through the Ras/phosphatidylinositol 3-kinase/Rac1 pathway in NIH3T3 cells. Evidence for association with reactive oxygen species.The p53-regulated cyclin-dependent kinase inhibitor, p21 (cip1, waf1, sdi1), is not required for global genomic and transcription-coupled nucleotide excision repair of UV-induced DNA photoproducts.p21(waf1/cip1)-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites.Human cells deficient in p53 regulated p21(waf1/cip1) expression exhibit normal nucleotide excision repair of UV-induced DNA damage.E2F regulates DDB2: consequences for DNA repair in Rb-deficient cells.Zebrafish (Danio rerio) life-cycle exposure to chronic low doses of ethinylestradiol modulates p53 gene transcription within the gonads, but not NER pathways.
P2860
Q24315840-76C29716-2552-49AF-A8B0-2CFFBB36C290Q27004135-C943DFFB-71FF-4036-9E88-6E7DB7E5591CQ28073944-02EBC00A-053C-4FB1-87A1-CA6B2BC686FFQ34394902-1D770657-A5C0-444F-9973-CE87F5ECAC3EQ34464861-5647478C-5DD7-42E0-90B9-1445FDA3D6ECQ35041627-6D8D2327-3474-4BFE-A2FD-ACFBAFB1EBA5Q36528506-66362EFC-B962-451B-BDC4-5D018AD8D1F0Q37748663-C663709A-C5F4-42B5-BD65-DCF56E23C3CCQ38307731-384396CE-257A-4890-8665-80FAA1F5C0E7Q40673701-D7D7839D-3E49-45AB-9D2A-E982DB9776A7Q40722141-D4F63EC2-BEDB-4631-B019-8BD9656BCD3AQ40746048-888D4F89-50E5-48B7-AC3A-64B8BE603681Q40809068-5BEE961B-82E8-4F26-8741-AEA7253C8503Q40810986-A25599A6-4799-4CD5-973B-ED882A5CAC6AQ43918561-68DE0EF0-4EF1-4A25-BADF-88343E8032E2Q53582492-FB10533B-53EF-42D6-837D-6AB695C6ADA5Q54312369-518FD7CA-6E4D-42DE-9798-12555423D949
P2860
Decreased DNA repair efficiency by loss or disruption of p53 function preferentially affects removal of cyclobutane pyrimidine dimers from non-transcribed strand and slow repair sites in transcribed strand.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
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2000年学术文章
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2000年學術文章
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name
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@en
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@nl
type
label
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@en
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@nl
prefLabel
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@en
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@nl
P2093
P2860
P356
P1476
Decreased DNA repair efficienc ...... r sites in transcribed strand.
@en
P2093
P2860
P304
11492-11497
P356
10.1074/JBC.275.15.11492
P407
P577
2000-04-01T00:00:00Z