IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage.
about
Regulation of immunity and oncogenesis by the IRF transcription factor familyProtein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling.Cutting edge: IRF8 regulates Bax transcription in vivo in primary myeloid cellsMolecular control of monocyte developmentInterferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCORMultiple Ets factors and interferon regulatory factor-4 modulate CD68 expression in a cell type-specific mannerHierarchical differentiation of myeloid progenitors is encoded in the transcription factor networkShared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell developmentInterferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPSInterferon regulatory factor-8-driven myeloid differentiation is regulated by 12/15-lipoxygenase-mediated redox signaling.Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis.Gamma interferon triggers interaction between ICSBP (IRF-8) and TEL, recruiting the histone deacetylase HDAC3 to the interferon-responsive element.The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemiaGranulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.Infection-induced myelopoiesis during intracellular bacterial infection is critically dependent upon IFN-γ signaling.A negative feedback loop of transcription factors specifies alternative dendritic cell chromatin States.Differential requirement for irf8 in formation of embryonic and adult macrophages in zebrafish.Identification of target genes and a unique cis element regulated by IRF-8 in developing macrophages.A panorama of lineage-specific transcription in hematopoiesis.Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein.Genetic variation associated with circulating monocyte count in the eMERGE NetworkIRF8 regulates B-cell lineage specification, commitment, and differentiation.Relevance of Interferon Regulatory Factor-8 Expression in Myeloid-Tumor Interactions.ICSBP-mediated immune protection against BCR-ABL-induced leukemia requires the CCL6 and CCL9 chemokinesMyeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axisM-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells.Hematopoietic cytokine-induced transcriptional regulation and Notch signaling as modulators of MDSC expansion.Regulation of monocyte differentiation by specific signaling modules and associated transcription factor networks.From proliferation to proliferation: monocyte lineage comes full circle.Regulation of myelopoiesis by the transcription factor IRF8.2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.Mechanisms overseeing myeloid-derived suppressor cell production in neoplastic disease.Interferon regulatory factor-8 is indispensable for the expression of promyelocytic leukemia and the formation of nuclear bodies in myeloid cells.Impaired myelopoiesis in mice devoid of interferon regulatory factor 1.The Granulocyte Progenitor Stage Is a Key Target of IRF8-Mediated Regulation of Myeloid-Derived Suppressor Cell Production.Association of MicroRNA-618 Expression With Altered Frequency and Activation of Plasmacytoid Dendritic Cells in Patients With Systemic Sclerosis.Inhibition of IRF8 Negatively Regulates Macrophage Function and Impairs Cutaneous Wound Healing.Transcriptional Regulation of Emergency Granulopoiesis in Leukemia.
P2860
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P2860
IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
IFN consensus sequence binding ...... toward the macrophage lineage.
@en
IFN consensus sequence binding ...... toward the macrophage lineage.
@nl
type
label
IFN consensus sequence binding ...... toward the macrophage lineage.
@en
IFN consensus sequence binding ...... toward the macrophage lineage.
@nl
prefLabel
IFN consensus sequence binding ...... toward the macrophage lineage.
@en
IFN consensus sequence binding ...... toward the macrophage lineage.
@nl
P2093
P1476
IFN consensus sequence binding ...... toward the macrophage lineage.
@en
P2093
Hideki Tsujimura
Keiko Ozato
Tokiko Nagamura-Inoue
Tomohiko Tamura
P304
P356
10.4049/JIMMUNOL.169.3.1261
P407
P577
2002-08-01T00:00:00Z