Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
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NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligandsA new human NHERF1 mutation decreases renal phosphate transporter NPT2a expression by a PTH-independent mechanismIRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+/H+ exchanger NHE3 and activates NHE3 activity in response to calciumSp1 and Sp3 control constitutive expression of the human NHE2 promoter by interactions with the proximal promoter and the transcription initiation siteMolecular mechanisms and regulation of urinary acidificationEzrin is required for the functional regulation of the epithelial sodium proton exchanger, NHE3Proximal nephronDefective coupling of apical PTH receptors to phospholipase C prevents internalization of the Na+-phosphate cotransporter NaPi-IIa in Nherf1-deficient micePostnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochleaSodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidneyLongitudinal study of urinary excretion of phosphate, calcium, and uric acid in mutant NHERF-1 null miceProteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule.Effects of ACE inhibition on proximal tubule sodium transport.Differential roles of NHERF1, NHERF2, and PDZK1 in regulating CFTR-mediated intestinal anion secretion in mice.Proteomic analysis of brush-border membrane vesicles isolated from purified proximal convoluted tubules.NHERF2/NHERF3 protein heterodimerization and macrocomplex formation are required for the inhibition of NHE3 activity by carbachol.Dynamics of PTH-induced disassembly of Npt2a/NHERF-1 complexes in living OK cells.Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null miceAstrocytic and neuronal localization of the scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF-2) in mouse brain.NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity.Role of PDZK1 protein in apical membrane expression of renal sodium-coupled phosphate transporters.PDZ interactions and proximal tubular phosphate reabsorption.Regulation of ion transport by the NHERF family of PDZ proteins.PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes.NHERF and regulation of the renal sodium-hydrogen exchanger NHE3.NaPi-IIa and interacting partners.NHERF family and NHE3 regulation.The role of NHERF-1 in the regulation of renal proximal tubule sodium-hydrogen exchanger 3 and sodium-dependent phosphate cotransporter 2a.Protein/protein interactions (PDZ) in proximal tubules.The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity.NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormonesImpaired sodium excretion and increased blood pressure in mice with targeted deletion of renal epithelial insulin receptorNHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells.Signaling pathways utilized by PTH and dopamine to inhibit phosphate transport in mouse renal proximal tubule cells.Renal NHE3 and NaPi2 partition into distinct membrane domains.The tails of apical scaffolding proteins EBP50 and E3KARP regulate their localization and dynamics.NHERF2 is crucial in ERM phosphorylation in pulmonary endothelial cells.Renal proximal tubular reabsorption is reduced in adult spontaneously hypertensive rats: roles of superoxide and Na+/H+ exchanger 3Novel regulatory function for NHERF-1 in Npt2a transcription.Loss of NHERF-1 expression prevents dopamine-mediated Na-K-ATPase regulation in renal proximal tubule cells from rat models of hypertension: aged F344 rats and spontaneously hypertensive rats.
P2860
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P2860
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@en
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@nl
type
label
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@en
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@nl
prefLabel
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@en
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@nl
P2093
P2860
P1476
Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse.
@en
P2093
Deborah A Steplock
Edward J Weinman
James B Wade
Richard A Coleman
Rochelle Cunningham
Shirish Shenolikar
Thomas L Pallone
Whaseon Lee-Kwon
P2860
P304
P356
10.1152/AJPCELL.00092.2003
P577
2003-08-13T00:00:00Z