A mechanism for Ikaros regulation of human globin gene switching.
about
Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongationZinc coordination is required for and regulates transcription activation by Epstein-Barr nuclear antigen 1Eos negatively regulates human γ-globin gene transcription during erythroid differentiation.3D shortcuts to gene regulationDistinctive patterns of evolution of the δ-globin gene (HBD) in primatesSelf-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros.Long-range chromosomal interactions and gene regulationIkaros controls isotype selection during immunoglobulin class switch recombination.Persistent fetal gamma-globin expression in adult transgenic mice following deletion of two silencer elements located 3' to the human Agamma-globin gene.Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150Towards a genome-wide reconstruction of cis-regulatory networks in the human genome.Advances in the understanding of haemoglobin switching.Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells.Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cellsNormal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutationsIkaros and GATA-1 combinatorial effect is required for silencing of human gamma-globin genes.Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch.
P2860
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P2860
A mechanism for Ikaros regulation of human globin gene switching.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
A mechanism for Ikaros regulation of human globin gene switching.
@en
A mechanism for Ikaros regulation of human globin gene switching.
@nl
type
label
A mechanism for Ikaros regulation of human globin gene switching.
@en
A mechanism for Ikaros regulation of human globin gene switching.
@nl
prefLabel
A mechanism for Ikaros regulation of human globin gene switching.
@en
A mechanism for Ikaros regulation of human globin gene switching.
@nl
P2093
P2860
P50
P1476
A mechanism for Ikaros regulation of human globin gene switching
@en
P2093
Janelle R Keys
Job Dekker
Karin M Gaensler
Michael R Tallack
Peter Papathanasiou
P2860
P304
P356
10.1111/J.1365-2141.2008.07065.X
P407
P577
2008-03-03T00:00:00Z