Stochastic gating and drug-ribosome interactions. - Wikidata - awgldk - TriplyDB

Stochastic gating and drug-ribosome interactions.

Stochastic gating and drug-ribosome interactions.

http://www.wikidata.org/entity/Q52591449

about

Dynamics, flexibility and ligand-induced conformational changes in biological macromolecules: a computational approach Steric interactions lead to collective tilting motion in the ribosome during mRNA-tRNA translocation Free State Conformational Sampling of the SAM-I Riboswitch Aptamer Domain Molecular sensing by the aptamer domain of the FMN riboswitch: a general model for ligand binding by conformational selection Interplay of the bacterial ribosomal A-site, S12 protein mutations and paromomycin binding: a molecular dynamics study.Aminoglycoside activity observed on single pre-translocation ribosome complexes.Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data.Magnesium fluctuations modulate RNA dynamics in the SAM-I riboswitch.Understanding the origins of bacterial resistance to aminoglycosides through molecular dynamics mutational study of the ribosomal A-site.Navigating the ribosome's metastable energy landscape Structural analysis of base substitutions in Thermus thermophilus 16S rRNA conferring streptomycin resistance.Connecting energy landscapes with experimental rates for aminoacyl-tRNA accommodation in the ribosome.A computational investigation on the connection between dynamics properties of ribosomal proteins and ribosome assembly Carbohydrate force fields Electrostatic interactions in aminoglycoside-RNA complexes.Nucleotide modifications and tRNA anticodon-mRNA codon interactions on the ribosome Excited states of ribosome translocation revealed through integrative molecular modeling.Molecular dynamics simulations of large macromolecular complexes.Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions Highly sampled tetranucleotide and tetraloop motifs enable evaluation of common RNA force fields.Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis.Sizing up long non-coding RNAs: do lncRNAs have secondary and tertiary structure?Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations.Key intermolecular interactions in the E. coli 70S ribosome revealed by coarse-grained analysis.Computational studies of molecular machines: the ribosome.Simulating activity of the bacterial ribosome.Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble.Selection of peptides that target the aminoacyl-tRNA site of bacterial 16S ribosomal RNA.Structure and mechanical properties of the ribosomal L1 stalk three-way junction.Flipping of the ribosomal A-site adenines provides a basis for tRNA selection.RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview.Aminoglycoside activity observed on single pre-translocation ribosome complexes

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P2860

Stochastic gating and drug-ribosome interactions.

http://www.wikidata.org/entity/Q52591449

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

@zh-hant

name

Stochastic gating and drug-ribosome interactions.

@en

Stochastic gating and drug-ribosome interactions.

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type

label

Stochastic gating and drug-ribosome interactions.

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Stochastic gating and drug-ribosome interactions.

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prefLabel

Stochastic gating and drug-ribosome interactions.

@en

Stochastic gating and drug-ribosome interactions.

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J.JMB.2008.12.035

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Journal of Molecular Biology

P1476

Stochastic gating and drug-ribosome interactions.

@en

P2093

Andrea C Vaiana

http://www.w3.org/2001/XMLSchema#string

Kevin Y Sanbonmatsu

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P2860

Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

Structure of the 30S ribosomal subunit

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Recognition of cognate transfer RNA by the 30S ribosomal subunit

Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site

Selection of tRNA by the ribosome requires a transition from an open to a closed form

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA

Structure of the 70S ribosome complexed with mRNA and tRNA

UCSF Chimera--a visualization system for exploratory research and analysis

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648-661

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scholarly article

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10.1016/J.JMB.2008.12.035

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2008-12-24T00:00:00Z

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19146858

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5970275

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