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Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor proteinTyrosylprotein sulfotransferase: purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteinsTwo heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombinDetection and purification of tyrosine-sulfated proteins using a novel anti-sulfotyrosine monoclonal antibody.Identification and characterization of tyrosylprotein sulfotransferase from human saliva.Design and evaluation of novel bivalent thrombin inhibitors based on amidinophenylalaninesThe refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsCrystal Structure of a Biosynthetic Sulfo-hirudin Complexed to ThrombinCrystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin InhibitorsTherapeutic target-site variability in α1-antitrypsin characterized at high resolutionBeyond heparinization: design of highly potent thrombin inhibitors suitable for surface couplingLoop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in ThrombinAccelerating the Association of the Most Stable Protein-Ligand Complex by More than Two Orders of MagnitudeMolecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegansThe phosphatidylethanolamine-binding protein is the prototype of a novel family of serine protease inhibitorsThe biology and enzymology of protein tyrosine O-sulfationClot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitorsExosite-driven substrate specificity and function in coagulationThrombin-specific inhibition by and slow cleavage of hirulog-1Structure of a serpin-enzyme complex probed by cysteine substitutions and fluorescence spectroscopy.The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsinLack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal spermProton bridging in the interactions of thrombin with hirudin and its mimics.Dipetalogastin, a potent thrombin inhibitor from the blood-sucking insect. Dipetalogaster maximus cDNA cloning, expression and characterization.New bivalent thrombin inhibitors with N(alpha)(methyl)arginine at the P1-position.Emerging anticoagulant and thrombolytic drugs.Delayed thrombin generation is not associated with fibrinopeptide formation during prolonged cardiopulmonary bypass with hirudin anticoagulation.Biophysical investigation of GpIbalpha binding to thrombin anion binding exosite II.From natural to synthetic multisite thrombin inhibitors.The conformations of hirudin in solution: a study using nuclear magnetic resonance, distance geometry and restrained molecular dynamics.Mutagenesis and evolution of sulfated antibodies using an expanded genetic code.Transition modes in Ising networks: an approximate theory for macromolecular recognition.The human estrogen sulfotransferase: a half-site reactive enzyme.In vitro selection of highly modified cyclic peptides that act as tight binding inhibitors.Thrombin-inhibiting nanoparticles rapidly constitute versatile and detectable anticlotting surfaces.Heparin-mimetic sulfated peptides with modulated affinities for heparin-binding peptides and growth factors.The role of protease-activated receptor-1 in bone healing.Total synthesis of homogeneous variants of hirudin P6: a post-translationally modified anti-thrombotic leech-derived protein.Principles underlying the use of conjunctive agents with plasminogen activators.Automated prediction of protein association rate constants.
P2860
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P2860
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
Kinetics of the inhibition of thrombin by hirudin.
@en
Kinetics of the inhibition of thrombin by hirudin.
@nl
type
label
Kinetics of the inhibition of thrombin by hirudin.
@en
Kinetics of the inhibition of thrombin by hirudin.
@nl
prefLabel
Kinetics of the inhibition of thrombin by hirudin.
@en
Kinetics of the inhibition of thrombin by hirudin.
@nl
P356
P1433
P1476
Kinetics of the inhibition of thrombin by hirudin.
@en
P2093
Hofsteenge J
P304
P356
10.1021/BI00364A025
P407
P577
1986-08-01T00:00:00Z