Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

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http://www.wikidata.org/entity/Q52678164
Oximes: inhibitors of human recombinant acetylcholinesterase. A structure-activity relationship (SAR) studyDesign, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.Mini review on blood-brain barrier penetration of pyridinium aldoximes.The present approaches to the development of prophylactic and therapeutic antidotes against nerve agents.Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.In vitro reactivation kinetics of paraoxon- and DFP-inhibited electric eel AChE using mono- and bis-pyridinium oximes.New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.In vitro oxime-assisted reactivation of paraoxon-inhibited human acetylcholinesterase and butyrylcholinesterase.A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice.Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide--a new nerve agent reactivator.
P2860

Novel series of bispyridinium compounds bearing a (Z)-but-2-ene linker--synthesis and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Item
http://www.wikidata.org/entity/Q52678164
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Novel series of bispyridinium ...... nhibited acetylcholinesterase.
@en
Novel series of bispyridinium compounds bearing a
@nl
type
label
Novel series of bispyridinium ...... nhibited acetylcholinesterase.
@en
Novel series of bispyridinium compounds bearing a
@nl
prefLabel
Novel series of bispyridinium ...... nhibited acetylcholinesterase.
@en
Novel series of bispyridinium compounds bearing a
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Novel series of bispyridinium ...... inhibited acetylcholinesterase
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2007.03.025
P407
P433
P478
P50
P577
P698