about
Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease riskProprotein convertase subtilisin/kexin type 9: from the discovery to the development of new therapies for cardiovascular diseasesThe UCL low-density lipoprotein receptor gene variant database: pathogenicity updateLiving the PCSK9 adventure: from the identification of a new gene in familial hypercholesterolemia towards a potential new class of anticholesterol drugs.Familial hypercholesterolemia: Molecular characterization of possible cases from the Azores Islands (Portugal).The importance of an integrated analysis of clinical, molecular, and functional data for the genetic diagnosis of familial hypercholesterolemia.Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.PCSK9: a convertase that coordinates LDL catabolism.Mutations and polymorphisms in the proprotein convertase subtilisin kexin 9 (PCSK9) gene in cholesterol metabolism and disease.Cardiovascular risk assessment of dyslipidemic children: analysis of biomarkers to identify monogenic dyslipidemia.Strategies for proprotein convertase subtilisin kexin 9 modulation: a perspective on recent patents.The role of proprotein convertase subtilisin/kexin type 9 in hyperlipidemia: focus on therapeutic implications.Proprotein convertase subtilisin / kexin 9 (PCSK9) inhibitors and the future of dyslipidemia therapy: an updated patent review (2011-2015).The Proprotein Convertases in Hypercholesterolemia and Cardiovascular Diseases: Emphasis on Proprotein Convertase Subtilisin/Kexin 9.Functional analysis of sites within PCSK9 responsible for hypercholesterolemia.Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradationFunctional characterization of splicing and ligand-binding domain variants in the LDL receptor.Reverse cascade screening for familial hypercholesterolemia in high-risk Chinese families.PCSK9 as a therapeutic target of dyslipidemiaThe evaluation of cascade testing for familial hypercholesterolemia
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Familial hypercholesterolaemia in Portugal.
@en
Familial hypercholesterolaemia in Portugal.
@nl
type
label
Familial hypercholesterolaemia in Portugal.
@en
Familial hypercholesterolaemia in Portugal.
@nl
prefLabel
Familial hypercholesterolaemia in Portugal.
@en
Familial hypercholesterolaemia in Portugal.
@nl
P2093
P1433
P1476
Familial hypercholesterolaemia in Portugal.
@en
P2093
A K Soutar
A M Medeiros
Investigators of Portuguese FH Study
P304
P356
10.1016/J.ATHEROSCLEROSIS.2007.07.019
P577
2007-08-31T00:00:00Z