Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.

Item
http://www.wikidata.org/entity/Q52962324
Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesINPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas.INPP4B is an oncogenic regulator in human colon cancer.Transforming Growth Factor-β Signaling Guides the Differentiation of Innate Lymphoid Cells in Salivary Glands.The extended human PTPome: a growing tyrosine phosphatase family.INPP4B-mediated DNA repair pathway confers resistance to chemotherapy in acute myeloid leukemia.Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia.Resistance of leukemia cells to cytarabine chemotherapy is mediated by bone marrow stroma, involves cell-surface equilibrative nucleoside transporter-1 removal and correlates with patient outcome.INPP5E Preserves Genomic Stability through Regulation of Mitosis.HBV infection potentiates resistance to S-phase arrest-inducing chemotherapeutics by inhibiting CHK2 pathway in diffuse large B-cell lymphoma.INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia.SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML.INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway.
P2860

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.

Item
http://www.wikidata.org/entity/Q52962324
description
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name
Inositol polyphosphate 4-phosp ...... tance and poor outcome in AML.
@en
Inositol polyphosphate 4-phosphatase II
@nl
type
label
Inositol polyphosphate 4-phosp ...... tance and poor outcome in AML.
@en
Inositol polyphosphate 4-phosphatase II
@nl
prefLabel
Inositol polyphosphate 4-phosp ...... tance and poor outcome in AML.
@en
Inositol polyphosphate 4-phosphatase II
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Inositol polyphosphate 4-phosp ...... stance and poor outcome in AML
@en
P2093
P304
P31
P356
10.1182/BLOOD-2014-09-603555
P407
P433
P478
P50
P577
P698