A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
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Therapeutic aspects of c-MYC signaling in inflammatory and cancerous colonic diseasesSIRT2 Expression Is Higher in Uveal Melanoma than In Ocular MelanocytesO-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway.Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.Expression profile of SIRT2 in human melanoma and implications for sirtuin-based chemotherapy.Profiling of human epigenetic regulators using a semi-automated real-time qPCR platform validated by next generation sequencing.Sirtuins in Skin and Skin Cancers.A variant in SIRT2 gene 3'-UTR is associated with susceptibility to colorectal cancer.Protein biomarkers predictive for response to anti-EGFR treatment in RAS wild-type metastatic colorectal carcinoma.SIRT6 haploinsufficiency induces BRAF melanoma cell resistance to MAPK inhibitors via IGF signalling
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A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
description
2014 nî lūn-bûn
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name
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@en
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@nl
type
label
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@en
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@nl
prefLabel
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@en
A chromatin modifier genetic s ...... lation of MEK kinase activity.
@nl
P2093
P2860
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A chromatin modifier genetic s ...... lation of MEK kinase activity.
@en
P2093
A Prahallad
H Horlings
I Nagtegaal
R Beijersbergen
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P2888
P304
P356
10.1038/ONC.2013.588
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P577
2014-01-27T00:00:00Z