Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
about
Oxidative Stress Signaling in Alzheimers DiseaseAlpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brainMemory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acidIntracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification.Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALSOxidative stress and mitochondrial dysfunction in Alzheimer's disease.Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.Synergy between the C2 allele of transferrin and the C282Y allele of the haemochromatosis gene (HFE) as risk factors for developing Alzheimer's disease.Oxidative damage to RNA: mechanisms, consequences, and diseases.An assay for RNA oxidation induced abasic sites using the Aldehyde Reactive ProbeIs Alzheimer's disease a mitochondrial disorder?RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria.Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain.Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice.Association between frontal cortex oxidative damage and beta-amyloid as a function of age in Down syndrome.Therapeutic potential of oxidant mechanisms in Alzheimer's disease.Association between urinary markers of nucleic acid oxidation and mortality in type 2 diabetes: a population-based cohort study.4-Hydroxyhexenal (HHE) impairs glutamate transport in astrocyte culturesMarkers of oxidant stress that are clinically relevant in aging and age-related diseaseOxidatively modified RNA in mild cognitive impairment.Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain.Battle against RNA oxidation: molecular mechanisms for reducing oxidized RNA to protect cells.Amyloid-β production: major link between oxidative stress and BACE1.Oxidative stress in Alzheimer's disease: Primary villain or physiological by-product?Corticotropin-releasing factor receptor-1 modulates biomarkers of DNA oxidation in Alzheimer's disease mice.Oxidative Stress Induced Mitochondrial Failure and Vascular Hypoperfusion as a Key Initiator for the Development of Alzheimer Disease.Oxidative stress mediates tau-induced neurodegeneration in DrosophilaQuantification of oxidized levels of specific RNA species using an aldehyde reactive probe.Histochemical accumulation of oxidative damage products is associated with Alzheimer-like pathology in the canine.Oxidative Stress and Balance in Neurodegenerative Diseases
P2860
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P2860
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@en
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@nl
type
label
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@en
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@nl
prefLabel
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@en
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@nl
P2093
P2860
P1476
Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.
@en
P2093
P2860
P304
P356
10.1111/J.1749-6632.1999.TB07855.X
P50
P577
1999-01-01T00:00:00Z