Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.
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Lipid matrix plays a role in Abeta fibril kinetics and morphologyThe coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathwayAn aminopeptidase from Streptomyces sp. KK565 degrades beta amyloid monomers, oligomers and fibrilsApolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapyAmyloid beta-protein stimulates trafficking of cholesterol and caveolin-1 from the plasma membrane to the Golgi complex in mouse primary astrocytesProtein phosphatase 5 protects neurons against amyloid-beta toxicityA capillary electrophoresis method for evaluation of Abeta proteolysis in vitroKnockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal NeurogenesisMetals and amyloid-beta in Alzheimer's diseaseHuman serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanismDifferential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cellsLipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's diseaseAmyloid beta-protein monomer folding: free-energy surfaces reveal alloform-specific differencesStabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptideReversal of long-term dendritic spine alterations in Alzheimer disease modelsEffects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicityTargeting amyloid-beta in glaucoma treatment.Interleukin 1 receptor antagonist knockout mice show enhanced microglial activation and neuronal damage induced by intracerebroventricular infusion of human beta-amyloid.Drug Development in Alzheimer's Disease: The Contribution of PET and SPECTThe Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer's DiseaseTDP-43: a new player on the AD field?Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: new knowledge from single-molecule fluorescence studiesInteraction between prion protein and Aβ amyloid fibrils revisitedDimer formation enhances structural differences between amyloid β-protein (1-40) and (1-42): an explicit-solvent molecular dynamics studyStress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease.Intracellular cleavage of amyloid β by a viral protease NIa prevents amyloid β-mediated cytotoxicityStructural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseYeast Ste23p shares functional similarities with mammalian insulin-degrading enzymes.Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid betaModulating self-assembly of amyloidogenic proteins as a therapeutic approach for neurodegenerative diseases: strategies and mechanismsEctoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's beta-amyloidStructural investigation of the C-terminal catalytic fragment of presenilin 1Protein misfolding and aggregation in Alzheimer's disease and type 2 diabetes mellitusResveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aβ and Aβ-metal complexes toxicityFingolimod phosphate attenuates oligomeric amyloid β-induced neurotoxicity via increased brain-derived neurotrophic factor expression in neuronsVirtual and In Vitro Screens Reveal a Potential Pharmacophore that Avoids the Fibrillization of Aβ1-42Geniposide Protects Primary Cortical Neurons against Oligomeric Aβ1-42-Induced Neurotoxicity through a Mitochondrial PathwayThe molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteinsModels of membrane-bound Alzheimer's Abeta peptide assembliesAlzheimer's associated β-amyloid protein inhibits influenza A virus and modulates viral interactions with phagocytes.
P2860
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P2860
Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@en
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@nl
type
label
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@en
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@nl
prefLabel
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@en
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@nl
P2093
P356
P1476
Oligomeric and fibrillar speci ...... lly affect neuronal viability.
@en
P2093
Arlene M Manelli
Grant A Krafft
Karie N Dahlgren
Lorinda K Baker
Mary Jo LaDu
W Blaine Stine
P304
32046-32053
P356
10.1074/JBC.M201750200
P407
P577
2002-06-10T00:00:00Z