Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
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Nuclear receptors and epigenetic regulation: opportunities for nutritional targeting and disease preventionBile acid nuclear receptor FXR and digestive system diseasesBile acid dysregulation, gut dysbiosis, and gastrointestinal cancer.FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.Src-mediated cross-talk between farnesoid X and epidermal growth factor receptors inhibits human intestinal cell proliferation and tumorigenesis.Colorectal Cancer-Associated Fibroblasts are Genotypically Distinct.Microbes, microbiota, and colon cancer.Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinomaHepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1α regulation of FXR expressionFXR and liver carcinogenesisMembrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemiaFXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression.Potential therapeutic targets of Guggulsterone in cancerBile acid transporters and regulatory nuclear receptors in the liver and beyondClinical significance of farnesoid X receptor expression in thyroid neoplasia.microRNA-192 suppresses the expression of the farnesoid X receptor.The expanding role of the bile acid receptor farnesoid X in the intestine and its potential clinical implications.Differential regulation of intestinal efflux transporters by pregnancy in mice.FXR silencing in human colon cancer by DNA methylation and KRAS signaling.Waltonitone inhibits proliferation of hepatoma cells and tumorigenesis via FXR-miR-22-CCNA2 signaling pathwayEnhanced expression of farnesoid X receptor in human hepatocellular carcinoma.Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis.Aldehyde Dehydrogenase 1 Expression Predicts Chemoresistance and Poor Clinical Outcomes in Patients with Locally Advanced Cervical Cancer Treated with Neoadjuvant Chemotherapy Prior to Radical Hysterectomy.Farnesoid X Receptor Expression in Microscopic Colitis: A Potential Role in Disease Etiopathogenesis.Inactivation of Adenomatous Polyposis Coli Reduces Bile Acid/Farnesoid X Receptor Expression through Fxr gene CpG Methylation in Mouse Colon Tumors and Human Colon Cancer Cells.Farnesoid X receptor expression is decreased in colonic mucosa of patients with primary sclerosing cholangitis and colitis-associated neoplasia.Bile acid-induced expression of farnesoid X receptor as the basis for superiority of internal biliary drainage in experimental biliary obstruction
P2860
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P2860
Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Expression of the nuclear bile ...... ciated with adverse prognosis.
@en
Expression of the nuclear bile ...... ciated with adverse prognosis.
@nl
type
label
Expression of the nuclear bile ...... ciated with adverse prognosis.
@en
Expression of the nuclear bile ...... ciated with adverse prognosis.
@nl
prefLabel
Expression of the nuclear bile ...... ciated with adverse prognosis.
@en
Expression of the nuclear bile ...... ciated with adverse prognosis.
@nl
P2093
P2860
P356
P1476
Expression of the nuclear bile ...... ciated with adverse prognosis.
@en
P2093
Andrea Berghold
Anton Berger
Dagmar Silbert
Georg Schauer
Kurt Prein
Magdalena Kapitan
Michael Trauner
Sigurd Lax
P2860
P304
P356
10.1002/IJC.26293
P577
2011-10-20T00:00:00Z