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A gene expression profile of stem cell pluripotentiality and differentiation is conserved across diverse solid and hematopoietic cancersRepression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferationTrim24 targets endogenous p53 for degradationA genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 networkThe first 30 years of p53: growing ever more complexPAX3-FOXO1 fusion gene in rhabdomyosarcomaPharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyp53 suppresses muscle differentiation at the myogenin step in response to genotoxic stressStructural Basis for ASPP2 Recognition by the Tumor Suppressor p73Next-generation sequencing of acute myeloid leukemia identifies the significance of TP53, U2AF1, ASXL1, and TET2 mutationsAlternative splicing targeting the hTAF4-TAFH domain of TAF4 represses proliferation and accelerates chondrogenic differentiation of human mesenchymal stem cellsDesign, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 InteractionSPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63p73 as a pharmaceutical target for cancer therapyASPP2 suppresses squamous cell carcinoma via RelA/p65-mediated repression of p63Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesisTP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent mannerOne-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.In vivo analysis of p53 tumor suppressor function using genetically engineered mouse modelsThe role of mutant p53 in human cancer.Nucleolar stress with and without p53.microRNA expression and biogenesis in cellular response to ionizing radiationRegulation of p53 is critical for vertebrate limb regeneration.A p53-Pax2 pathway in kidney development: implications for nephrogenesis.Beclin-1-p53 interaction is crucial for cell fate determination in embryonal carcinoma cells.Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.Circadian clock, cancer, and chemotherapy.p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor.Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis.Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.Ganoderma lucidum Polysaccharides Induce Macrophage-Like Differentiation in Human Leukemia THP-1 Cells via Caspase and p53 Activation.Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter.p53 downregulates Down syndrome-associated DYRK1A through miR-1246.Clinical therapy using iPSCs: hopes and challengesPeriosteal osteosarcoma: a review of clinical evidenceDNA mismatch repair network gene polymorphism as a susceptibility factor for pancreatic cancerDNA mismatch repair gene polymorphisms affect survival in pancreatic cancer.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
The p53 family in differentiation and tumorigenesis.
@en
The p53 family in differentiation and tumorigenesis.
@nl
type
label
The p53 family in differentiation and tumorigenesis.
@en
The p53 family in differentiation and tumorigenesis.
@nl
prefLabel
The p53 family in differentiation and tumorigenesis.
@en
The p53 family in differentiation and tumorigenesis.
@nl
P356
P1476
The p53 family in differentiation and tumorigenesis
@en
P2093
Thorsten Stiewe
P2888
P304
P356
10.1038/NRC2072
P407
P577
2007-02-01T00:00:00Z