MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.
about
MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expressionPrognostic importance of MN1 transcript levels, and biologic insights from MN1-associated gene and microRNA expression signatures in cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B studyThe leukemia-associated fusion protein MN1-TEL blocks TEL-specific recognition sequences.Mapping of MN1 sequences necessary for myeloid transformation.Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers.The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice.Meningioma 1 is required for appropriate osteoblast proliferation, motility, differentiation, and function.Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia.
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MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice.
description
2006 nî lūn-bûn
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name
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
@en
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
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type
label
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
@en
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
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prefLabel
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
@en
MN1-TEL, the product of the t( ...... es myeloid malignancy in mice.
@nl
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MN1-TEL, the product of the t( ...... ses myeloid malignancy in mice
@en
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10.1038/SJ.LEU.2404298
P577
2006-06-29T00:00:00Z