Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas.
about
BMP and TGFbeta pathways in human central chondrosarcoma: enhanced endoglin and Smad 1 signaling in high grade tumors.Chondrosarcoma: with updates on molecular genetics.Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferationFGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.Cellular/intramuscular myxoma and grade I myxofibrosarcoma are characterized by distinct genetic alterations and specific composition of their extracellular matrixCentral chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro.No preclinical rationale for IGF1R directed therapy in chondrosarcoma of boneTargeting the apoptotic pathway in chondrosarcoma using recombinant human Apo2L/TRAIL (dulanermin), a dual proapoptotic receptor (DR4/DR5) agonist.Loss of β-catenin induces multifocal periosteal chondroma-like masses in miceAberrant heparan sulfate proteoglycan localization, despite normal exostosin, in central chondrosarcoma.Src kinases in chondrosarcoma chemoresistance and migration: dasatinib sensitises to doxorubicin in TP53 mutant cells.Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome.PTHR1 mutations associated with Ollier disease result in receptor loss of function.Profiling of high-grade central osteosarcoma and its putative progenitor cells identifies tumourigenic pathways.Biomarkers of Osteosarcoma, Chondrosarcoma, and Ewing Sarcoma.Exploring the key genes and pathways in enchondromas using a gene expression microarray.Molecular basis of differentiation therapy for soft tissue sarcomas.Identification of novel biomarker candidates for immunohistochemical diagnosis to distinguish low-grade chondrosarcoma from enchondroma.Patched-one or smoothened gene mutations are infrequent in chondrosarcoma.CORR Insights®: Is Needle Biopsy Clinically Useful in Preoperative Grading of Central Chondrosarcoma of the Pelvis and Long Bones?TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cellsGenetic alterations in chondrosarcomas - keys to targeted therapies?Bcl-xl as the most promising Bcl-2 family member in targeted treatment of chondrosarcomaThe Role of EXT1 in Nonhereditary Osteochondroma: Identification of Homozygous Deletions
P2860
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P2860
Absence of IHH and retention of PTHrP signalling in enchondromas and central chondrosarcomas.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Absence of IHH and retention o ...... s and central chondrosarcomas.
@en
Absence of IHH and retention o ...... s and central chondrosarcomas.
@nl
type
label
Absence of IHH and retention o ...... s and central chondrosarcomas.
@en
Absence of IHH and retention o ...... s and central chondrosarcomas.
@nl
prefLabel
Absence of IHH and retention o ...... s and central chondrosarcomas.
@en
Absence of IHH and retention o ...... s and central chondrosarcomas.
@nl
P2093
P2860
P356
P1476
Absence of IHH and retention o ...... s and central chondrosarcomas.
@en
P2093
Anne-Marie Cleton-Jansen
Anthonie H M Taminiau
Judith V M G Bovée
Leida B Rozeman
Liesbeth Hameetman
Pancras C W Hogendoorn
P2860
P304
P356
10.1002/PATH.1723
P577
2005-03-01T00:00:00Z