about
The yeast coexpression network has a small-world, scale-free architecture and can be explained by a simple modelLarge-scale cDNA transfection screening for genes related to cancer development and progressionNarrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypesGenome-wide screening for gene function using RNAi in mammalian cells.An in vivo functional genetic screen reveals a role for the TRK-T3 oncogene in tumor progression.Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells.shRNA-mediated RNA interference as a tool for genetic synthetic lethality screening in mouse embryo fibroblasts.Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of functionA library of gene expression signatures to illuminate normal and pathological lymphoid biology.shRNA libraries and their use in cancer genetics.Generation of RNAi libraries for high-throughput screens.pHUSH: a single vector system for conditional gene expressionThe full-ORF clone resource of the German cDNA ConsortiumDesigner siRNAs to overcome the challenges from the RNAi pathway.Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysisPooled RNAi Screens - Technical and Biological Aspects.TOPS: a versatile software tool for statistical analysis and visualization of combinatorial gene-gene and gene-drug interaction screens.Making sense of cancer genomic data.Kinase requirements in human cells: V. Synthetic lethal interactions between p53 and the protein kinases SGK2 and PAK3Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation.Functional interrogation of breast cancer: from models to drugs.Cancer metastasis therapeutic targets and drug discovery: emerging small-molecule protein kinase inhibitors.Optimizing RNA interference for application in mammalian cells.Improving the efficiency of RNA interference in mammals.Building mammalian signalling pathways with RNAi screens.Dissecting cancer pathways and vulnerabilities with RNAi.Bcl-2 is a critical mediator of intestinal transformationNatural killer cells: versatile roles in autoimmune and infectious diseases.Towards systematic functional characterization of cancer genomes.Molecular mechanisms of natural killer cell activation in response to cellular stress.Characterization of BCAR4, a novel oncogene causing endocrine resistance in human breast cancer cells.Biological functions of the genes in the mammaprint breast cancer profile reflect the hallmarks of cancer.Molecular determinants of chemotherapy resistance in ovarian cancer.Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
New tools for functional mammalian cancer genetics.
@en
New tools for functional mammalian cancer genetics.
@nl
type
label
New tools for functional mammalian cancer genetics.
@en
New tools for functional mammalian cancer genetics.
@nl
prefLabel
New tools for functional mammalian cancer genetics.
@en
New tools for functional mammalian cancer genetics.
@nl
P356
P1476
New tools for functional mammalian cancer genetics.
@en
P2093
René Bernards
Thijn R Brummelkamp
P2888
P304
P356
10.1038/NRC1191
P407
P577
2003-10-01T00:00:00Z