Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry.
about
Multiple NSAID-induced hits injure the small intestine: underlying mechanisms and novel strategiesUnderstanding and modulating mammalian-microbial communication for improved human health.Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of DiclofenacPharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice.Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokineticsAcute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice.Transformation of diclofenac in hybrid biofilm-activated sludge processes.Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice.Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.Potential protective effect of sunitinib after administration of diclofenac: biochemical and histopathological drug-drug interaction assessment in a mouse model.Lumiracoxib metabolism in male C57bl/6J mice: characterisation of novel in vivo metabolites.Role of enterohepatic recirculation in drug disposition: cooperation and complications.Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice.Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice.The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac.Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid
P2860
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P2860
Diclofenac metabolism in the mouse: novel in vivo metabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@en
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@nl
type
label
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@en
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@nl
prefLabel
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@en
Diclofenac metabolism in the m ...... ar ion trap mass spectrometry.
@nl
P2093
P2860
P1433
P1476
Diclofenac metabolism in the m ...... ear ion trap mass spectrometry
@en
P2093
Chris Page
Kathryn Pickup
Sunil Sarda
Timothy Schulz-Utermoehl
P2860
P304
P356
10.3109/00498254.2011.607865
P407
P50
P577
2011-09-28T00:00:00Z