COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.
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Cullin-RING ubiquitin ligases: global regulation and activation cyclesAssociation of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosomeCOP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phaseCOP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulationThe Arabidopsis COP9 Signalosome Subunit 7 Is a Model PCI Domain Protein with Subdomains Involved in COP9 Signalosome AssemblyERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentThe Evolution of COP9 Signalosome in Unicellular and Multicellular OrganismsLight signal transduction: an infinite spectrum of possibilitiesThe minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domainCOP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.Drosophila COP9 signalosome subunit 7 interacts with multiple genomic loci to regulate development.C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissuesAnalysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2.Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice.Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in miceThe eta7/csn3-3 auxin response mutant of Arabidopsis defines a novel function for the CSN3 subunit of the COP9 signalosome.Hepatic deficiency of COP9 signalosome subunit 8 induces ubiquitin-proteasome system impairment and Bim-mediated apoptosis in murine livers.Revisiting the COP9 signalosome as a transcriptional regulator.Neddylation and deneddylation in cardiac biologyRegulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modificationsThe tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.The COP9 signalosome and cullin-RING ligases in the heartCSN6 deregulation impairs genome integrity in a COP1-dependent pathwayCOP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity.Knockdown of subunit 3 of the COP9 signalosome inhibits C2C12 myoblast differentiation via NF-KappaB signaling pathwayCOP9 signalosome subunit 6 (CSN6) regulates E6AP/UBE3A in cervical cancer.The organization of a CSN5-containing subcomplex of the COP9 signalosome.THE COP9 SIGNALOSOME, A NOVEL, ESSENTIAL REGULATOR OF SKELETAL DEVELOPMENT AND TUMORIGENESIS.DCAF1 controls T-cell function via p53-dependent and -independent mechanismsCSN5 specifically interacts with CDK2 and controls senescence in a cytoplasmic cyclin E-mediated manner.RETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.CSN6 positively regulates c-Jun in a MEKK1-dependent manner.Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing TranscriptionThe COP9 signalosome negatively regulates proteasome proteolytic function and is essential to transcription.The discovery of a reciprocal relationship between tyrosine-kinase signaling and cullin neddylationThe receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.The COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice.COP9 signalosome function in the DDR.Roles of COP9 signalosome in cancer.
P2860
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P2860
COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@en
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@nl
type
label
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@en
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@nl
prefLabel
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@en
COP9 signalosome subunit 8 is ...... he cell cycle from quiescence.
@nl
P2093
P356
P1433
P1476
COP9 signalosome subunit 8 is ...... the cell cycle from quiescence
@en
P2093
Huiyong Zhang
Richard A Flavell
Suchithra Menon
Xing Wang Deng
P2860
P304
P356
10.1038/NI1514
P407
P50
P577
2007-09-30T00:00:00Z