Selected-fit versus induced-fit protein binding: kinetic differences and mutational analysis.
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HDAC8 substrates: Histones and beyondProtein flexibility in docking and surface mappingConformational selection in protein binding and functionTrapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysisInsights in 17beta-HSD1 enzyme kinetics and ligand binding by dynamic motion investigationOne-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologueStructure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis .A Selection Fit Mechanism in BMP Receptor IA as a Possible Source for BMP Ligand-Receptor PromiscuitypH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding MechanismSingle amino acid exchange in bacteriophage HK620 tailspike protein results in thousand-fold increase of its oligosaccharide affinityBiochemical Basis for Dominant Inheritance, Variable Penetrance, and Maternal Effects in RBP4 Congenital Eye DiseaseA role for both conformational selection and induced fit in ligand binding by the LAO proteinA unified conformational selection and induced fit approach to protein-peptide dockingCharacterizing changes in the rate of protein-protein dissociation upon interface mutation using hotspot energy and organizationHow to Distinguish Conformational Selection and Induced Fit Based on Chemical Relaxation RatesThe role of dynamic conformational ensembles in biomolecular recognitionExcited protein states of human tear lipocalin for low- and high-affinity ligand binding revealed by functional AB loop motion.Molecular simulations illuminate the role of regulatory components of the RNA polymerase from the hepatitis C virus in influencing protein structure and dynamicsCooperativity dominates the genomic organization of p53-response elements: a mechanistic viewMolecular dynamics simulation of phosphorylated KID post-translational modification.Induced fit or conformational selection for RNA/U1A foldingSubstrate-induced changes in protease active site conformation impact on subsequent reactions with substrates.Polymorphism in Alzheimer Abeta amyloid organization reflects conformational selection in a rugged energy landscape.Kinetic rate constant prediction supports the conformational selection mechanism of protein binding.Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC)Allosteric suppression of HIV-1 reverse transcriptase structural dynamics upon inhibitor bindingUbiquitin dynamics in complexes reveal molecular recognition mechanisms beyond induced fit and conformational selection.Structure-based modeling of protein: DNA specificity.Induced fit, conformational selection and independent dynamic segments: an extended view of binding eventsGlobal conformational selection and local induced fit for the recognition between intrinsic disordered p53 and CBPEffect of short- and long-range interactions on trp rotamer populations determined by site-directed tryptophan fluorescence of tear lipocalinAllosteric regulation of pathologic angiogenesis: potential application for angiogenesis-related blindness.Efficient incorporation of protein flexibility and dynamics into molecular docking simulationsEvolutionary Conserved Positions Define Protein Conformational DiversityEnzymatic detoxication, conformational selection, and the role of molten globule active sites.Conformational selection is a dominant mechanism of ligand bindingThermodynamic basis for the optimization of binding-induced biomolecular switches and structure-switching biosensors.Conformational selection and induced fit mechanism underlie specificity in noncovalent interactions with ubiquitin.Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase.
P2860
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P2860
Selected-fit versus induced-fit protein binding: kinetic differences and mutational analysis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Selected-fit versus induced-fi ...... ences and mutational analysis.
@en
Selected-fit versus induced-fi ...... ences and mutational analysis.
@nl
type
label
Selected-fit versus induced-fi ...... ences and mutational analysis.
@en
Selected-fit versus induced-fi ...... ences and mutational analysis.
@nl
prefLabel
Selected-fit versus induced-fi ...... ences and mutational analysis.
@en
Selected-fit versus induced-fi ...... ences and mutational analysis.
@nl
P2860
P356
P1433
P1476
Selected-fit versus induced-fi ...... ences and mutational analysis.
@en
P2093
Carola von Deuster
Thomas R Weikl
P2860
P304
P356
10.1002/PROT.22223
P407
P577
2009-04-01T00:00:00Z