Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT. - Wikidata - awgldk - TriplyDB

Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

http://www.wikidata.org/entity/Q53576595

about

Immortalization of Primary Keratinocytes and Its Application to Skin Research Functional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells In vitro cell transformation assays for an integrated, alternative assessment of carcinogenicity: a data-based analysis.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Establishment of functioning human corneal endothelial cell line with high growth potential.ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells Efficient immortalization of primary nasopharyngeal epithelial cells for EBV infection study.The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs.Regulation of Notch1 gene expression by p53 in epithelial cells A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro GLI1 orchestrates CXCR4/CXCR7 signaling to enhance migration and metastasis of breast cancer cells.Novel human bronchial epithelial cell lines for cystic fibrosis research.One-step immortalization of primary human airway epithelial cells capable of oncogenic transformation.Extremely stringent activation of p16INK4a prevents immortalization of uterine cervical epithelial cells without human papillomavirus oncogene expression.Polycomb group proteins are key regulators of keratinocyte function Alternatives to the carcinogenicity bioassay for toxicity prediction: are we there yet?Predicting the carcinogenicity of chemicals with alternative approaches: recent advances.GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.Immortalization of pig fibroblast cells by transposon-mediated ectopic expression of porcine telomerase reverse transcriptase Characterization of immortalized dairy goat male germline stem cells (mGSCs).Isogenic human mammary epithelial cell lines: novel tools for target identification and validation. Comprehensive characterization of an isogenic human mammary epithelial cell model provides evidence for epithelial-mesenchymal transition.Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells.Enhanced specificity of HPV16 E6E7 siRNA by RNA-DNA chimera modification.CDK4 and cyclin D1 allow human myogenic cells to recapture growth property without compromising differentiation potential.How to measure RNA expression in rare senescent cells expressing any specific protein such as p16Ink4a.Immortalization of bovine mammary epithelial cells alone by human telomerase reverse transcriptase.Early growth response-1 mediates downregulation of telomerase in cervical cancer.Inhibition of beta-TrCP function potentiates UVB-induced apoptosis in hTERT-immortalized normal human keratinocytes.ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes.Characterization of immortalized human mammary epithelial cell line HMEC 2.6.Reversible differentiation of immortalized human bladder smooth muscle cells accompanied by actin bundle reorganization.Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.Induction of Non-Apoptotic Programmed Cell Death by Oncogenic RAS in Human Epithelial Cells and Its Suppression by MYC Overexpression.A novel method to generate single-cell-derived cancer-associated fibroblast clones.Alternative Toxicity Testing: Analyses on Skin Sensitization, ToxCast Phases I and II, and Carcinogenicity Provide Indications on How to Model Mechanisms Linked to Adverse Outcome Pathways.Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.Molecular mechanisms of cellular senescence and immortalization of human cells.

P2860

Q26786026-CE62427A-F404-4EAF-95C9-9CB2E3EF16C4 Q28590071-8B1BE8FC-8EA6-4E66-A624-44D39E7F8A32 Q30576475-F44E3EE8-6618-4280-ACDF-3459A10FCCD5 Q31115332-33209410-2A16-477A-97E5-A9099F8EDB01 Q33808862-207B473E-33E7-442E-A33C-542403B68E07 Q34140233-70AF2B4A-1174-4E89-99FB-E7C933281EF4 Q34242167-955469C8-D6FB-4355-90A2-8D6C89736295 Q35027926-F4C36B91-C21C-4E1C-AE83-77631B97AF14 Q35133043-D3EA2FBD-3DA9-4B02-9BBD-EEC1C44EAD79 Q35380984-7A8F39A0-9240-4E7B-8B91-99B86CD358D8 Q35621829-0FEFE1D4-E9A3-49B8-AA40-37A929FDFFB3 Q35856917-539B397B-10DC-4B8F-82A0-59B07AD0B72C Q36394208-08C0D3B7-4C35-46DC-A4CF-AA5FA4B4F1A0 Q36545242-7D0A223E-39E4-42EC-A112-9FF79879A824 Q37086280-804E496A-DBCC-47AA-B09B-A4A61E648F6B Q37410396-97BE1913-7BF1-4E14-AFD2-19E4E710826E Q37564524-2E0F07F1-2927-40C6-8C4B-83C24C986D6F Q37810463-8A34C52C-C414-4966-AC89-F429A9F37F30 Q37987563-7F79B18C-D294-49DD-AFBD-63702A4C5DB3 Q38223908-F668CD1E-EDCF-468D-B042-4E4658F5F708 Q38730588-2847301E-2098-4072-B5CE-CF38F43A7649 Q38837779-8A250B61-F18D-4571-AB3E-BE964CEC6ACC Q39009191-45EF2AAB-4F25-4768-9018-56C35238D97A Q39181989-05867A2C-C695-455B-A34F-A2D2CE03A4F4 Q39381110-4980CD74-3B2A-403E-9973-9BCD5C7E187D Q39527299-0CD94E5F-385A-4837-95F8-A080137E5872 Q39559082-4E402107-2A64-4562-9A29-67A38E202D09 Q39579087-0F50F5A4-E43C-43AD-9702-E21CEBC9F746 Q39736670-0245DE6E-CA10-446F-B1FC-3A4791AD8D29 Q39984972-A10CC489-DA99-44F0-AC50-8F77E66B1088 Q40022422-514A9B5B-EFDB-452F-B19B-A8BBD6D278DB Q42317566-8A07B90A-BB00-4439-91BB-5C1F16BC9D68 Q42516678-508ABDDE-3122-475E-A1B0-C94DA4C22C54 Q43289917-DB477D6E-6E13-4B17-A467-6D29C0E5A00D Q44573227-58730D2C-6954-48A1-8DD6-5D2572BF43A6 Q50140924-4E93C86F-6E11-46B8-92CA-8D2022451085 Q51079254-71B8933B-0900-4242-A84E-0DF84D67ECF0 Q52663769-D97190DF-F3BA-4D54-9DB0-7311CEFC9CCB Q53314163-63A9B23E-3CC0-4D1B-B435-A0B21CD044AF Q53515893-E25D76C9-A65A-4B00-9EDA-C66F7AC779BE

P2860

Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

http://www.wikidata.org/entity/Q53576595

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh-hant

name

Efficient immortalization of p ...... ed with introduction of hTERT.

@en

Efficient immortalization of p ...... ed with introduction of hTERT.

@nl

type

label

Efficient immortalization of p ...... ed with introduction of hTERT.

@en

Efficient immortalization of p ...... ed with introduction of hTERT.

@nl

prefLabel

Efficient immortalization of p ...... ed with introduction of hTERT.

@en

Efficient immortalization of p ...... ed with introduction of hTERT.

@nl

P1433

Q53576595-896229D3-0D2A-4A2B-B881-54FE946CE86A

P1476

Q53576595-67C88913-0E12-41DF-90AD-BDA9D2E73C27

P2093

Q53576595-19FA5A37-684B-48EB-A2B5-33F920A8C371

Q53576595-41FDC333-85BA-4EC2-904A-ABB14B37E86C

Q53576595-93887953-BC98-484D-91CC-C8D516F2FC1E

Q53576595-E6133B44-181B-4CF4-A67D-B65026ECF47E

Q53576595-ED87E8EE-7595-4C39-AF98-FE220380B495

Q53576595-EFD56356-5EEF-498C-8170-02B514CEC1C7

Q53576595-FC1E0576-87A1-4875-BC3C-9501218A2D86

P2860

Q53576595-032A9EEE-C682-4AE5-971C-BDBFE67BE0BF

Q53576595-06178AB9-8050-4851-9C1E-54EF94710945

Q53576595-062CD04B-9408-4EC6-8365-5319ED0EC6F8

Q53576595-0A2BB897-6B39-4E88-A570-12543BE0AD62

Q53576595-0B537BD3-8FC8-4C12-9117-96B485162D0A

Q53576595-0C03A15C-21BA-484E-B8B1-BC71D42B0364

Q53576595-284B8728-7AAB-4CFE-8BFB-5F8ECD2B64F6

Q53576595-31BEBB48-1447-481C-8441-5857061299D7

Q53576595-39560CC3-3A60-434E-8D82-3BAD4D09CFB5

Q53576595-452EA5BF-65BA-4A3E-A3BD-970FE267ACF8

P304

Q53576595-EAE4345A-D990-44FC-829A-9A6A33381E54

P31

Q53576595-4A4F698F-3A99-4EC4-B7F6-39F514800988

P356

Q53576595-25BDC8C5-A52F-45EF-86CA-178F85DDE475

P433

Q53576595-756C58C7-9E6D-4273-AD68-70E7307D92AF

P478

Q53576595-84B11393-D96E-4043-B0CD-8FC1BBCDCECF

P50

Q53576595-2B2C8BB1-2974-419C-8163-299F7433135F

P577

Q53576595-A22DB46C-02C6-47E3-B450-6768F77CC3EF

P5875

Q53576595-9AD10499-EB8D-4F31-86DB-54DC49410A43

P698

Q53576595-62557049-BA60-4873-AEF5-CCBDF5AAC00A

P356

J.1349-7006.2006.00373.X

P1433

P1476

Efficient immortalization of p ...... ed with introduction of hTERT.

@en

P2093

Denise A Galloway

http://www.w3.org/2001/XMLSchema#string

Kei Haga

http://www.w3.org/2001/XMLSchema#string

Mako Narisawa-Saito

http://www.w3.org/2001/XMLSchema#string

Michiie Sakamoto

http://www.w3.org/2001/XMLSchema#string

Shin-ichi Ohno

http://www.w3.org/2001/XMLSchema#string

Takashi Yugawa

http://www.w3.org/2001/XMLSchema#string

Tohru Kiyono

http://www.w3.org/2001/XMLSchema#string

P2860

Extension of life-span by introduction of telomerase into normal human cells

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

p16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells.

Polycomb CBX7 has a unifying role in cellular lifespan

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

P304

147-154

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1111/J.1349-7006.2006.00373.X

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

98

http://www.w3.org/2001/XMLSchema#string

P50

Masatoshi Fujita

P577

2007-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6568600

http://www.w3.org/2001/XMLSchema#string

P698

17233832

http://www.w3.org/2001/XMLSchema#string