Centrosome polarization delivers secretory granules to the immunological synapse.
about
Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systemsSlp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapseActivation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrinDynamic Regulation of TCR-Microclusters and the Microsynapse for T Cell ActivationComparative Anatomy of Phagocytic and Immunological SynapsesCytotoxic granule secretion by lymphocytes and its link to immune homeostasisLysosome-Related Effector Vesicles in T Lymphocytes and NK CellsRegulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmCell biological steps and checkpoints in accessing NK cell cytotoxicityCell polarisation and the immunological synapseMolecular regulation of CRAC channels and their role in lymphocyte functionT-cells play the classics with a different spinMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseHuman T-lymphotropic virus-1 visualized at the virological synapse by electron tomographyDistinct Roles of Cytoskeletal Components in Immunological Synapse Formation and Directed Secretion.Visualization of cytolytic T cell differentiation and granule exocytosis with T cells from mice expressing active fluorescent granzyme BThe centrosome is an actin-organizing centre.Impaired immunological synapse in sperm associated antigen 6 (SPAG6) deficient miceElastohydrodynamics and Kinetics of Protein Patterning in the Immunological SynapseDistinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cellsRemodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopyNatural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapseActin nucleation at the centrosome controls lymphocyte polarity.Natural killer cell signal integration balances synapse symmetry and migrationA major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion.Human cytomegalovirus infection elicits new decidual natural killer cell effector functions.The regulated secretory pathway in CD4(+) T cells contributes to human immunodeficiency virus type-1 cell-to-cell spread at the virological synapseCa2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor.The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesisDephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complexRegulation of the formation and trafficking of vesicles from Golgi by PCH family proteins during chemotaxisCentrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage.MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation.In vivo polarization of IFN-gamma at Kupfer and non-Kupfer immunological synapses during the clearance of virally infected brain cells.Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapseMyosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse.Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment.Proteomic characterization of plasma membrane-proximal T cell activation responses.Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters
P2860
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P2860
Centrosome polarization delivers secretory granules to the immunological synapse.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Centrosome polarization delivers secretory granules to the immunological synapse.
@en
Centrosome polarization delivers secretory granules to the immunological synapse.
@nl
type
label
Centrosome polarization delivers secretory granules to the immunological synapse.
@en
Centrosome polarization delivers secretory granules to the immunological synapse.
@nl
prefLabel
Centrosome polarization delivers secretory granules to the immunological synapse.
@en
Centrosome polarization delivers secretory granules to the immunological synapse.
@nl
P2093
P356
P1433
P1476
Centrosome polarization delivers secretory granules to the immunological synapse.
@en
P2093
Endre Majorovits
Giovanna Bossi
Jane C Stinchcombe
Stephen Fuller
P2888
P304
P356
10.1038/NATURE05071
P407
P577
2006-09-01T00:00:00Z
P6179
1001238123