C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.
about
Pro-inflammatory interleukin-18 increases Alzheimer's disease-associated amyloid-β production in human neuron-like cellsPAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor proteinCD74 interacts with APP and suppresses the production of AbetaBRI3 inhibits amyloid precursor protein processing in a mechanistically distinct manner from its homologue dementia gene BRI2An X11alpha/FSBP complex represses transcription of the GSK3beta gene promoterThe amyloid-beta precursor protein: integrating structure with biological functionGlycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeuticsSoluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APPClinical proteomics of enervated neuronsInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseThe multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foesAPP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammationAPP processing in Alzheimer's diseaseProteolytic processing of Alzheimer's β-amyloid precursor proteinThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseasePhenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cellsTransgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivoDexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcriptionFE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowthFE65 as a link between VLDLR and APP to regulate their trafficking and processingPresenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expressionβ-Amyloid impairs axonal BDNF retrograde trafficking.Hirano bodies differentially modulate cell death induced by tau and the amyloid precursor protein intracellular domain.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in DrosophilaS100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model.A novel function of the Fe65 neuronal adaptor in estrogen receptor action in breast cancer cellsAssociation of GSK3B with Alzheimer disease and frontotemporal dementiaTyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo.Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.Comparative transcriptome profiling of amyloid precursor protein family members in the adult cortexErythroid cell-specific alpha-globin gene regulation by the CP2 transcription factor family.AICD Overexpression in Neuro 2A Cells Regulates Expression of PTCH1 and TRPC5.Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model.Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice.Novel adaptors of amyloid precursor protein intracellular domain and their functional implications.The γ-secretase complex: from structure to function.Phosphorylation of amyloid precursor protein (APP) at Thr668 regulates the nuclear translocation of the APP intracellular domain and induces neurodegeneration.Amyloid precursor-like protein 2 C-terminal fragments upregulate S100A9 gene and protein expression in BV2 cells.Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty.A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
P2860
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P2860
C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@en
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@nl
type
label
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@en
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@nl
prefLabel
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@en
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@nl
P2093
P356
P1433
P1476
C-terminal fragments of amyloi ...... thase kinase-3beta expression.
@en
P2093
Cheol Hyoung Park
Eun-Mee Kim
Hye-Sun Kim
Jean-Pyo Lee
Ji-Heui Seo
Keun-A Chang
Seonghan Kim
Sung-Jin Jeong
Yoo-Hun Suh
P304
P356
10.1096/FJ.03-0106FJE
P407
P577
2003-08-15T00:00:00Z