A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
about
FOXP3 ensembles in T-cell regulationFE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4Structural basis for polyproline recognition by the FE65 WW domainThe amyloid-beta precursor protein: integrating structure with biological functionThe amyloid precursor protein: beyond amyloidInsights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's diseaseStress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytesCrystal structure of the human Fe65-PTB1 domainTip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylationProteolytic processing of Alzheimer's β-amyloid precursor proteinNeprilysin activity and expression are controlled by nicastrinEssential roles for the FE65 amyloid precursor protein-interacting proteins in brain developmentDexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcriptionSERCA pump activity is physiologically regulated by presenilin and regulates amyloid beta production.Structural and functional characterization of a novel FE65 protein product up-regulated in cognitively impaired FE65 knockout mice.Dysregulation of Ca2+ signaling in astrocytes from mice lacking amyloid precursor protein.Tip60 HAT Action Mediates Environmental Enrichment Induced Cognitive Restoration.Tip off the HAT- Epigenetic control of learning and memory by Drosophila Tip60Amyloid precursor protein and BACE function as oligomers.Novel modulators of amyloid-beta precursor protein processing.Amyloid precursor protein and presenilin involvement in cell signaling.A TAG on to the neurogenic functions of APPPresenilin: RIP and beyond.Systematic evaluation of candidate ligands regulating ectodomain shedding of amyloid precursor protein.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseaseThe tale of protein lysine acetylation in the cytoplasm.Biology and pathophysiology of the amyloid precursor protein.The physiology of the β-amyloid precursor protein intracellular domain AICD.Physiological functions of APP family proteins.Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling.Fe65 matters: new light on an old molecule.Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis.An AICD-based functional screen to identify APP metabolism regulators.Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin.High intracellular concentrations of amyloid-beta block nuclear translocation of phosphorylated CREB.Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes.Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation.The amyloid precursor protein intracellular domain-fe65 multiprotein complexes: a challenge to the amyloid hypothesis for Alzheimer's disease?Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment.Inverse and distinct modulation of tau-dependent neurodegeneration by presenilin 1 and amyloid-beta in cultured cortical neurons: evidence that tau phosphorylation is the limiting factor in amyloid-beta-induced cell death.
P2860
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P2860
A {gamma}-secretase-independent mechanism of signal transduction by the amyloid precursor protein.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@ast
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@en
type
label
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@ast
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@en
prefLabel
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@ast
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@en
P2860
P356
P1476
A {gamma}-secretase-independen ...... the amyloid precursor protein.
@en
P2093
Bruce A Yankner
Matthew R Hass
P2860
P304
36895-36904
P356
10.1074/JBC.M502861200
P407
P577
2005-08-15T00:00:00Z