The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.
about
Prostaglandin E receptor type 4-associated protein interacts directly with NF-kappaB1 and attenuates macrophage activationGPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushingMixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanesNon-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?A subpopulation of smooth muscle cells, derived from melanocyte-competent precursors, prevents patent ductus arteriosusGenetic and pharmacological analysis of prostanoid receptor functionPharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptorFunction of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxinThe prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressureActivation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregationReceptors for prostaglandin E(2) that regulate cellular immune responses in the mouseMetabolism of PGE2 by prostaglandin dehydrogenase is essential for remodeling the ductus arteriosusProstaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neuronsChronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosusImpaired bone resorption to prostaglandin E2 in prostaglandin E receptor EP4-knockout miceCyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdeltacPGES/p23 is required for glucocorticoid receptor function and embryonic growth but not prostaglandin E2 synthesisRegulation of the fetal mouse ductus arteriosus is dependent on interaction of nitric oxide and COX enzymes in the ductal wall.Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse modelsRole of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics.In vivo constriction of the fetal and neonatal ductus arteriosus by a prostanoid EP4-receptor antagonist in rats.Cyclooxygenase-dependent signalling: molecular events and consequences.Detection of QTL for traits related to adaptation to sub-optimal climatic conditions in chickens.Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms.Inhibition of cyclooxygenase isoforms in late- but not midgestation decreases contractility of the ductus arteriosus and prevents postnatal closure in mice.Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice.Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone.Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor.Not a mouse stirring: deletion of the EP2 and love's labor's lostSyndromic patent ductus arteriosus: evidence for haploinsufficient TFAP2B mutations and identification of a linked sleep disorder.Genetic analysis of fetal development and parturition control in the mouse.PGE₂ promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells.Impaired bone resorption by lipopolysaccharide in vivo in mice deficient in the prostaglandin E receptor EP4 subtype.Prostaglandin E2 promotes endothelial differentiation from bone marrow-derived cells through AMPK activationBiochemistry of cyclooxygenase (COX)-2 inhibitors and molecular pathology of COX-2 in neoplasia.Agonist-induced internalization and mitogen-activated protein kinase activation of the human prostaglandin EP4 receptor.Heterogeneity of genetic modifiers ensures normal cardiac developmentPatent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.Finding genetic contributions to sporadic disease: a recessive locus at 12q24 commonly contributes to patent ductus arteriosus.Prostanoid receptors: ontogeny and implications in vascular physiology.
P2860
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P2860
The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@en
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@nl
type
label
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@en
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@nl
prefLabel
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@en
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@nl
P2093
P356
P1433
P1476
The prostaglandin receptor EP4 ...... ardiovascular system at birth.
@en
P2093
Anderson PA
Camenisch T
Coffman TM
Snouwaert JN
P2888
P356
10.1038/36342
P407
P577
1997-11-01T00:00:00Z
P6179
1036127175