Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.
about
An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanismsThe role of X-chromosome inactivation in female predisposition to autoimmunityHuman leukocyte Antigen-DM polymorphisms in autoimmune diseasesRole of T cell-glial cell interactions in creating and amplifying central nervous system inflammation and multiple sclerosis disease symptomsOvarian autoimmune disease: clinical concepts and animal modelsLymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patientsAntigen Presentation, Autoantigens, and Immune Regulation in Multiple Sclerosis and Other Autoimmune DiseasesEnvironmental microbes and uveitis: is microbial exposure always bad?Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organsOligodendrocytes expressing exclusively the DM20 isoform of the proteolipid protein gene: myelination and developmentPositive and negative selection of the T cell repertoire: what thymocytes see (and don't see)Relapsing-remitting central nervous system autoimmunity mediated by GFAP-specific CD8 T cells.A molecular view of multiple sclerosis and experimental autoimmune encephalitis: what can we learn from the epitope data?An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide.Mechanisms of self-nonself discrimination and possible clinical relevance.Autoimmune T cell responses in the central nervous systemB cells participate in thymic negative selection of murine auto-reactive CD4+ T cellsIns2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin.Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II moleculeThe role of the thymus in tolerance.The genetics of the thyroid stimulating hormone receptor: history and relevanceTCR recognition of peptide/MHC class II complexes and superantigensControl of central and peripheral tolerance by Aire.Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells.Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopesT- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis.Lymphostromal interactions in thymic development and function.Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stageAlternative splicing in multiple sclerosis and other autoimmune diseases.Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23Immune tolerance in multiple sclerosis.Central tolerance mechanisms in control of susceptibility to autoimmune uveitic disease.Thymic selection revisited: how essential is it?Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor.Isolation, identification, and purification of murine thymic epithelial cells.Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice.Prophylactic cancer vaccination by targeting functional non-selfT-helper cell tolerance to ubiquitous nuclear antigens
P2860
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P2860
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@en
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@nl
type
label
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@en
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@nl
prefLabel
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@en
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@nl
P2093
P2860
P356
P1433
P1476
Shaping of the autoreactive T- ...... ed in thymic epithelial cells.
@en
P2093
P2860
P2888
P356
10.1038/71540
P407
P577
2000-01-01T00:00:00Z