Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage - Wikidata - awgldk - TriplyDB

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

http://www.wikidata.org/entity/Q34694319

about

Regulatory T-Cell Development in the Human Thymus Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms.Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals Dendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.CD4+CD25+ regulatory T cells in autoimmune arthritis.Rare development of Foxp3+ thymocytes in the CD4+CD8+ subset APECED: A Paradigm of Complex Interactions between Genetic Background and Susceptibility Factors Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.Intraclonal competition limits the fate determination of regulatory T cells in the thymus.Generation of Regulatory T Cells to Antigen Expressed in the Retina.The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development A role for the IkappaB family member Bcl-3 in the control of central immunologic tolerance The Attenuated Live Yellow Fever Virus 17D Infects the Thymus and Induces Thymic Transcriptional Modifications of Immunomodulatory Genes in C57BL/6 and BALB/C Mice.Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes.Differentiation of regulatory Foxp3+ T cells in the thymic cortex.Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo Advancements in immune tolerance Advances in type I diabetes associated tolerance mechanisms.Fetal exposure to high-avidity TCR ligand enhances expansion of peripheral T regulatory cells.Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.Differential requirement of PKC-theta in the development and function of natural regulatory T cells.Peripheral induction of tolerance by retinal antigen expression CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells.Thymic remodeling associated with hyperplasia in myasthenia gravis.Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations.Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model.Thymic regulatory T cell development: role of signalling pathways and transcription factors.Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.Influence of human myasthenia gravis thymus on the differentiation of human cord blood stem cells in SCID mice.Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development.Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells.The phenotype and activation status of regulatory T cells during Friend retrovirus infection.A specific signalling signature characterizes the development of naturally occurring and antigen-specific regulatory T cells.De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR.Thymic self-antigen expression for the design of a negative/tolerogenic self-vaccine against type 1 diabetes Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.Regulatory T cell development in the absence of functional Foxp3.The FOXP3+ subset of human CD4+CD8+ thymocytes is immature and subject to intrathymic selection.Differentiation of human thymic regulatory T cells at the double positive stage.

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Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage

http://www.wikidata.org/entity/Q34694319

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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label

Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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prefLabel

Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Proceedings of the National Academy of Sciences of the United States of America

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Foxp3+ CD25+ regulatory T cell ...... e double-positive thymic stage

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Abdelhadi Saoudi

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Fay Magnusson

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Julie Cabarrocas

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Khashayarsha Khazaie

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P2860

Control of regulatory T cell development by the transcription factor Foxp3

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Projection of an immunological self shadow within the thymus by the aire protein

Aire regulates negative selection of organ-specific T cells

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

Enterocolitis induced by autoimmune targeting of enteric glial cells: a possible mechanism in Crohn's disease?

Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

CD4+ CD25+ suppressor T cells: more questions than answers.

Myelin/oligodendrocyte glycoprotein-deficient (MOG-deficient) mice reveal lack of immune tolerance to MOG in wild-type mice.

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