Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain. - Wikidata - awgldk - TriplyDB

Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.

Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.

http://www.wikidata.org/entity/Q54106494

about

Cytoskeletal protein radixin activates integrin alpha(M)beta(2) by binding to its cytoplasmic tail CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units A glimpse of the ERM proteins Moesin controls clathrin-mediated S1PR1 internalization in T cells Sphingolipid regulation of ezrin, radixin, and moesin proteins family: implications for cell dynamics.The biology of extracellular vesicles with focus on platelet microparticles and their role in cancer development and progression Organizing the cell cortex: the role of ERM proteins Spatial localization of m-calpain to the plasma membrane by phosphoinositide biphosphate binding during epidermal growth factor receptor-mediated activation Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles Moesin regulates stable microtubule formation and limits retroviral infection in cultured cells.The cytoskeletal linker protein moesin: decreased levels in Wiskott-Aldrich syndrome platelets and identification of a cleavage pathway in normal platelets.Platelets mediate increased endothelium permeability in dengue through NLRP3-inflammasome activation.Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice.Binding of moesin and ezrin to membranes containing phosphatidylinositol (4,5) bisphosphate: a comparative study of the affinity constants and conformational changes.Alveolar echinococcosis: characterization of diagnostic antigen Em18 and serological evaluation of recombinant Em18.Nodes of Ranvier form in association with ezrin-radixin-moesin (ERM)-positive Schwann cell processes Imaging of T-cell interactions with antigen presenting cells in culture and in intact lymphoid tissue.The distal pole complex: a novel membrane domain distal to the immunological synapse.Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aα.Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes.Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion.Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.Ezrin and moesin function together to promote T cell activation.Local phosphocycling mediated by LOK/SLK restricts ezrin function to the apical aspect of epithelial cells Coordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activation Inhibition of calpain blocks platelet secretion, aggregation, and spreading Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-β signaling Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future?Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis.Ezrin is a negative regulator of death receptor-induced apoptosis.Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranes.Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member.The ERM Protein Moesin Regulates CD8(+) Regulatory T Cell Homeostasis and Self-Tolerance.Radixin stimulates Rac1 and Ca2+/calmodulin-dependent kinase, CaMKII: cross-talk with Galpha13 signaling.The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.First Case of X-Linked Moesin Deficiency Identified After Newborn Screening for SCID.Endothelial cell calpain activity facilitates lymphocyte diapedesis.Moesin-deficient mice reveal a non-redundant role for moesin in lymphocyte homeostasis.Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.

P2860

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P2860

Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its insensitivity to calpain.

http://www.wikidata.org/entity/Q54106494

description

1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年学术文章

@wuu

1999年学术文章

@zh-cn

1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

@zh

1999年學術文章

@zh-hant

name

Moesin, the major ERM protein ...... its insensitivity to calpain.

@en

Moesin, the major ERM protein ...... its insensitivity to calpain.

@nl

type

label

Moesin, the major ERM protein ...... its insensitivity to calpain.

@en

Moesin, the major ERM protein ...... its insensitivity to calpain.

@nl

prefLabel

Moesin, the major ERM protein ...... its insensitivity to calpain.

@en

Moesin, the major ERM protein ...... its insensitivity to calpain.

@nl

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S0014-5793(98)01674-3

P1433

P1476

Moesin, the major ERM protein ...... its insensitivity to calpain.

@en

P2093

A Bretscher

http://www.w3.org/2001/XMLSchema#string

A Shcherbina

http://www.w3.org/2001/XMLSchema#string

D M Kenney

http://www.w3.org/2001/XMLSchema#string

E Remold-O'Donnell

http://www.w3.org/2001/XMLSchema#string

P2860

Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events

Heterotypic and homotypic associations between ezrin and moesin, two putative membrane-cytoskeletal linking proteins

Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site

Moesin interacts with the cytoplasmic region of intercellular adhesion molecule-3 and is redistributed to the uropod of T lymphocytes during cell polarization

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Molecular cloning, cDNA sequence, and chromosomal assignment of the human radixin gene and two dispersed pseudogenes

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts.

Phosphorylation of threonine 558 in the carboxyl-terminal actin-binding domain of moesin by thrombin activation of human platelets.

ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transduction.

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31-36

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scholarly article

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10.1016/S0014-5793(98)01674-3

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1

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9928947

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