DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae.
about
Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cellsExtracellular signal-regulated kinase activates topoisomerase IIalpha through a mechanism independent of phosphorylation.Topoisomerase I is essential in Cryptococcus neoformans: role In pathobiology and as an antifungal target.The topoisomerase IIbeta circular clamp arrests transcription and signals a 26S proteasome pathwayPreclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases.Differential expression of topoisomerase I and RAD52 protein in yeast reveals new facets of the mechanism of action of bisdioxopiperazine compounds.Inhibition of topoisomerase II by ICRF-193 prevents efficient replication of herpes simplex virus type 1.Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53.
P2860
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P2860
DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae.
description
1995 nî lūn-bûn
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1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
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name
DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
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DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
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type
label
DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
@en
DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
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prefLabel
DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
@en
DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
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P2093
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DNA topoisomerase II is the mo ...... 3 in Saccharomyces cerevisiae.
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P2093
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1995-06-01T00:00:00Z