about
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium functionPI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growthThe Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.Receptor tyrosine kinases and TLR/IL1Rs unexpectedly activate myeloid cell PI3kγ, a single convergent point promoting tumor inflammation and progression.PI3K in cancer-stroma interactions: bad in seed and ugly in soil.Myocyte signalling in leucocyte recruitment to the heart.PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice.Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation.Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia.Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over timeRac signal adaptation controls neutrophil mobilization from the bone marrow.Distinct effects of leukocyte and cardiac phosphoinositide 3-kinase γ activity in pressure overload-induced cardiac failure.Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function.Phosphoinositide 3-Kinase Gamma Inhibition Protects from Anthracycline Cardiotoxicity and Reduces Tumor Growth.Somatic mutagenesis in satellite cells associates with human skeletal muscle aging.Morgana acts as an oncosuppressor in chronic myeloid leukemia.The absence of functional PI3Kgamma prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice.The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary ciliumWhole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell typeHealthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Irene Franco
@ast
Irene Franco
@en
Irene Franco
@es
Irene Franco
@nl
Irene Franco
@sl
type
label
Irene Franco
@ast
Irene Franco
@en
Irene Franco
@es
Irene Franco
@nl
Irene Franco
@sl
prefLabel
Irene Franco
@ast
Irene Franco
@en
Irene Franco
@es
Irene Franco
@nl
Irene Franco
@sl
P106
P21
P31
P496
0000-0002-4272-239X