The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages.
about
Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidationEndothelial cell-derived lipase mediates uptake and binding of high-density lipoprotein (HDL) particles and the selective uptake of HDL-associated cholesterol esters independent of its enzymic activityHydroxynonenal inactivates cathepsin B by forming Michael adducts with active site residues.Oxidized LDL: diversity, patterns of recognition, and pathophysiology.Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeInactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophagesLysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismRole of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?Chronically active: activation of microglial proteolysis in ageing and neurodegeneration.Smooth Muscle Cell Foam Cell Formation, Apolipoproteins, and ABCA1 in Intracranial Aneurysms: Implications for Lipid Accumulation as a Promoter of Aneurysm Wall Rupture.Autophagy is associated with cell fate in the process of macrophage-derived foam cells formation and progress.Medical bioremediation of age-related diseases.Target acquired: Selective autophagy in cardiometabolic disease.Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages.The effects of ascorbate and dehydroascorbate on the oxidation of low-density lipoprotein.Biochemistry and pathology of radical-mediated protein oxidation.Autophagy links inflammasomes to atherosclerotic progression.Greater selective uptake by Hep G2 cells of high-density lipoprotein cholesteryl ester hydroperoxides than of unoxidized cholesteryl esters.Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids.Hypochlorite-modified high density lipoprotein, a high affinity ligand to scavenger receptor class B, type I, impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins.Cyclodextrins differentially mobilize free and esterified cholesterol from primary human foam cell macrophages.Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets.Aggregated LDL and lipid dispersions induce lysosomal cholesteryl ester accumulation in macrophage foam cells.
P2860
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P2860
The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
The intracellular storage and ...... f oxidized LDL in macrophages.
@en
The intracellular storage and ...... f oxidized LDL in macrophages.
@nl
type
label
The intracellular storage and ...... f oxidized LDL in macrophages.
@en
The intracellular storage and ...... f oxidized LDL in macrophages.
@nl
prefLabel
The intracellular storage and ...... f oxidized LDL in macrophages.
@en
The intracellular storage and ...... f oxidized LDL in macrophages.
@nl
P2093
P1476
The intracellular storage and ...... f oxidized LDL in macrophages.
@en
P2093
P304
P356
10.1016/0005-2760(92)90287-6
P577
1992-06-01T00:00:00Z