Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

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http://www.wikidata.org/entity/Q54285483

Q54285483

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Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions Phytomelatonin: assisting plants to survive and thrive Local melatoninergic system as the protector of skin integrity Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model Cognitive deficits and anxiety induced by diisononyl phthalate in mice and the neuroprotective effects of melatonin.Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways Skin, reactive oxygen species, and circadian clocks.Potential impact of silymarin in combination with chlorogenic acid and/or melatonin in combating cardiomyopathy induced by carbon tetrachloride.Melatonin and atopy: role in atopic dermatitis and asthma Functions of melatonin in plants: a review.Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.Melatonin enhances photo-oxidation of 2',7'-dichlorodihydrofluorescein by an antioxidant reaction that renders N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK).N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.Topical Formulation Containing Naringenin: Efficacy against Ultraviolet B Irradiation-Induced Skin Inflammation and Oxidative Stress in Mice.Melatonin reverses H2 O2 -induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway.Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.Protective effects of extracts from Fructus rhodomyrti against oxidative DNA damage in vitro and in vivo Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation.Melatonin's protective effect against UV radiation: a systematic review of clinical and experimental studies.Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures.A review of metal-catalyzed molecular damage: protection by melatonin.Melatonin regulates mesenchymal stem cell differentiation: a review.Mitochondrial catastrophe during doxorubicin-induced cardiotoxicity: a review of the protective role of melatonin.Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.Melatonin and mitochondrial function during ischemia/reperfusion injury.Melatonin: the dawning of a treatment for fibrosis?Melatonin significantly improves the developmental competence of bovine somatic cell nuclear transfer embryos.Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.A review of the protective role of melatonin during phosphine-induced cardiotoxicity: focus on mitochondrial dysfunction, oxidative stress and apoptosis.Neuroprotective Mechanisms of Melatonin in Hemorrhagic Stroke.Melatonin: A pleiotropic molecule that modulates DNA damage response and repair pathways.Exogenous Melatonin Improves Antioxidant Defense in Cucumber Seeds (Cucumis sativus L.) Germinated under Chilling Stress.A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells.Mice Brain Tissue Injury Induced by Diisononyl Phthalate Exposure and the Protective Application of Vitamin E.Melatonin Application to Pisum sativum L. Seeds Positively Influences the Function of the Photosynthetic Apparatus in Growing Seedlings during Paraquat-Induced Oxidative Stress.Melatonin Reduces Oxidative Stress Damage Induced by Hydrogen Peroxide in Saccharomyces cerevisiae.Melatonin treatment induces apoptosis through regulating the nuclear factor-κB and mitogen-activated protein kinase signaling pathways in human gastric cancer SGC7901 cells.Role of melatonin receptor MT(2) and quinone reductase II in the regulation of the redox status of 3T3-L1 preadipocytes in vitro.Attenuation of ultraviolet A-induced alterations in NIH3T3 dermal fibroblasts by melatonin.Melatonin at pharmacological concentrations suppresses osteoclastogenesis via the attenuation of intracellular ROS.

P2860

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P2860

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

Item

http://www.wikidata.org/entity/Q54285483

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

@en

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

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type

Item

label

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

@en

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

@nl

prefLabel

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

@en

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

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P1476

Melatonin enhances antioxidati ...... nosine) in ex vivo human skin.

@en

P2093

Konrad Kleszczyński

http://www.w3.org/2001/XMLSchema#string

Lena H Hardkop

http://www.w3.org/2001/XMLSchema#string

Nathalie Kruse

http://www.w3.org/2001/XMLSchema#string

Tobias W Fischer

http://www.w3.org/2001/XMLSchema#string

P2860

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

Toxic effects of ultraviolet radiation on the skin

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis.

Melatonin preserves the transient mitochondrial permeability transition for protection during mitochondrial Ca(2+) stress in astrocyte.

Neuroendocrinology of the skin.

A survey of molecular details in the human pineal gland in the light of phylogeny, structure, function and chronobiological diseases.

Protein kinase D mediates mitochondrion-to-nucleus signaling and detoxification from mitochondrial reactive oxygen species.

Sensing the environment: regulation of local and global homeostasis by the skin's neuroendocrine system.

Melatonin, hydroxyl radical-mediated oxidative damage, and aging: a hypothesis.

P304

303-312

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scholarly article

P356

10.1111/JPI.12018

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Detlef Zillikens

P577

2012-10-30T00:00:00Z

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P5875

232740228

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23110400

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P921

melatonin

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

about

P2860

P2860

Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin.

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