Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10.
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Tumor-Induced Local and Systemic Impact on Blood Vessel FunctionMolecular characterization of circulating tumor cells in human metastatic colorectal cancerTIMP-1 promotes accumulation of cancer associated fibroblasts and cancer progression.CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasisHepatic stellate cells: central modulators of hepatic carcinogenesis.Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10.ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signalingReduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor ResistanceThe tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signalingOn the Pro-Metastatic Stress Response to Cancer Therapies: Evidence for a Positive Co-Operation between TIMP-1, HIF-1α, and miR-210Cytokine functions of TIMP-1.Molecular targets and pathways involved in liver metastasis of colorectal cancer.Premetastatic niche formation in the liver: emerging mechanisms and mouse models.Handling Metalloproteinases.TIMPs: versatile extracellular regulators in cancer.TIMP-1 signaling via CD63 triggers granulopoiesis and neutrophilia in mice.Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colonization in lung adenocarcinoma.Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis.Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAF (V600E) mutation status and together with hypoxia-related proteins predicts aggressive behavior.The MET Oncogene as a Therapeutical Target in Cancer Invasive Growth.New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.The hepatic pre-metastatic niche in pancreatic ductal adenocarcinoma.Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds
P2860
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P2860
Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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2011年學術文章
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2011年學術文章
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name
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@en
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@nl
type
label
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@en
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@nl
prefLabel
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@en
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@nl
P2093
P2860
P1476
Tumor cell-derived Timp-1 is n ...... ing via inhibition of Adam-10.
@en
P2093
Achim Krüger
Bastian Seubert
Florian Schelter
Martina Grandl
Michael Gerg
Stephanie Hauser
Susanne Schaten
P2860
P2888
P304
P356
10.1007/S10585-011-9410-Z
P577
2011-07-26T00:00:00Z