Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. - Wikidata - awgldk - TriplyDB

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

http://www.wikidata.org/entity/Q54483264

about

Phosphoinositide 3-kinase: friend and foe in cardiovascular disease Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.PI3K at the crossroads of tumor angiogenesis signaling pathways Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III phosphoinositide 3-kinase PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function Plastic roles of pericytes in the blood-retinal barrier.Endothelial permeability and VE-cadherin: a wacky comradeship.The pathobiology of vascular malformations: insights from human and model organism genetics.Class II phosphoinositide 3-kinases contribute to endothelial cells morphogenesis.Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation.PI3K in cancer: divergent roles of isoforms, modes of activation and therapeutic targeting.Xyloketal B attenuates atherosclerotic plaque formation and endothelial dysfunction in apolipoprotein e deficient mice.Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns.Tissue-specific epigenetics in gene neighborhoods: myogenic transcription factor genes.Neovascularization in the pulmonary endothelium is regulated by the endosome: Rab4-mediated trafficking and p18-dependent signaling.Inactivation of the Class II PI3K-C2β Potentiates Insulin Signaling and Sensitivity Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells Phosphatidylinositol 3-phosphates-at the interface between cell signalling and membrane traffic.Matricellular protein CCN3 mitigates abdominal aortic aneurysm.Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.Urokinase-type Plasminogen Activator (uPA) Promotes Angiogenesis by Attenuating Proline-rich Homeodomain Protein (PRH) Transcription Factor Activity and De-repressing Vascular Endothelial Growth Factor (VEGF) Receptor Expression.Classes of phosphoinositide 3-kinases at a glance.Gene delivery to Nile tilapia cells for transgenesis and the role of PI3K-c2α in angiogenesis Dynasore impairs VEGFR2 signalling in an endocytosis-independent manner.Targeting PI3K in Cancer: Any Good News?PI3K in cancer-stroma interactions: bad in seed and ugly in soil.Phosphoinositide 3-kinases as accelerators and brakes of autophagy.PI3K/AKT signaling pathway and cancer: an updated review.New insight into the intracellular roles of class II phosphoinositide 3-kinases.Role of phosphoinositide 3-kinase in the pathogenesis of acute pancreatitis.Crossroads of PI3K and Rac pathways.PI3K-C2α: One enzyme for two products coupling vesicle trafficking and signal transduction.Endothelial progenitor cells in tumor angiogenesis: another brick in the wall.PI3K/AKT Pathway and Its Mediators in Thyroid Carcinomas.Antiglioma effects of cytarabine on leptomeningeal metastasis of high-grade glioma by targeting the PI3K/Akt/mTOR pathway.Novel roles for class II Phosphoinositide 3-Kinase C2β in signalling pathways involved in prostate cancer cell invasion.Phosphatidylinositol-3-phosphate in the regulation of autophagy membrane dynamics.Ras guanyl nucleotide releasing protein 2 affects cell viability and cell-matrix adhesion in ECV304 endothelial cells.

P2860

Q26796228-0895F249-629B-497E-9034-18020605D575 Q27324465-1AFADFA2-FAF4-4B2D-8179-5E505F2A3BC4 Q28396795-DB79ECD6-15D8-46B3-AB00-EAC8041CCDA3 Q28506609-D13546E6-E12E-4478-9273-51149E653FD2 Q30427499-AABC28E5-5CB5-4B51-8FAE-4BD6AE44A97D Q33701751-F427E2D7-35E9-4F30-A810-6945C6375D90 Q33716453-E0DA3632-6775-4526-AA42-F78C73EEF92A Q33728179-4C2BB8E6-EBFA-47D3-B277-9C0E75D32105 Q34544980-CAD658B7-E8C4-4136-B106-9E8A0AA1868D Q34548346-60598230-9E59-4F8C-AE23-8933571E4F82 Q35140529-62EE07DE-C2D3-47D7-A000-D4901A9F8FE0 Q35260766-F9435814-1EE7-4F48-B6B4-48D41979383D Q35548908-A627ABF1-9617-4887-9FFD-09928059BAC7 Q35813677-EF985429-AE45-42A4-9478-1046869F590C Q35882604-5F6AF2BD-72F8-4EEE-97B5-E0B8E5DDDB76 Q36122879-DF075803-7862-4D10-B625-8FF89EB13E3A Q36363079-72E01BC9-C0C1-44AE-985E-F0DDD2706F19 Q36561963-AB369CF0-8835-419D-86DA-27DE7005D2A1 Q36712621-55B99414-7F2F-4E3E-B873-821A3460802B Q36737904-A903B357-7B3B-4C7B-B031-C71A965B15B2 Q36761235-D7844B63-3746-47C1-8F39-D45A1A634FA8 Q36990083-C5EE50FD-862A-4EBE-86BC-60980C0252AE Q37098900-9C3AF4C5-FE54-4077-AF74-835509FB4501 Q37608715-5E3F3E73-D6E0-40EB-ACEE-ED6927175639 Q37710895-F1D7DF8A-4650-4D08-BB37-6AD0241DA278 Q37715042-C9B8E698-D434-4C43-B4D7-6D29797B2B80 Q38105322-9F25CD1B-C4B7-461B-AEEE-B8BEED5A6192 Q38124762-3B020024-2C4A-4EE4-B5BF-8F96A665821E Q38129508-119BFCE4-FFB8-4010-B03E-A31E70B5E918 Q38217651-58FC05AA-D8E0-47CD-8983-1E8494AFB1E9 Q38252290-61CD4276-2B1B-4469-9790-F4B739D458D7 Q38266869-B257B264-F229-439F-A837-32214FE9995A Q38459968-2F6C9669-3246-4278-B414-DF80B34A6FD7 Q38483135-C03703E7-067B-4DF9-BF6A-D2990DA0CD51 Q38497288-753C1463-EAFB-4558-A840-8530E58F7E6C Q38644584-0ED2C516-5BD7-48A2-8AF2-6BD74EC60BD5 Q38696870-C281177D-9763-46F8-A72F-64B56C129729 Q38785807-1E2C6259-9371-44FA-88C9-E4C5D824AC93 Q39038475-7EA9F196-9685-43F6-8361-97D553E50E1D Q39170092-EA91FF8C-02BF-43DC-BCA5-696B595C0260

P2860

Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.

http://www.wikidata.org/entity/Q54483264

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@en

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@nl

type

label

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@en

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@nl

prefLabel

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@en

Endothelial PI3K-C2α, a class ...... and vascular barrier function.

@nl

P1433

Q54483264-54E4CC86-6D4C-4FCA-9E00-AEF7E2A2ED10

P1476

Q54483264-A7004BF0-D3C3-452C-8926-AAF66700DF16

P2093

Q54483264-04A78040-9281-4A33-9901-E49FB985AA55

Q54483264-0FB72A2B-2E39-4227-AD0D-1DAEFBD26E62

Q54483264-19D80ADB-2C85-4682-AE92-8F0B572314FB

Q54483264-2191D2F0-CED8-452A-A60F-1063A7AC24E2

Q54483264-39C2EB9C-2C4D-4A22-878D-D1D2C88C7D2E

Q54483264-428CA4BE-10D9-4A22-B3C3-377928B310F8

Q54483264-4ADC2F34-C537-46A7-93B4-4B37FAC6641F

Q54483264-5841CDAC-E8FF-4C15-B4D8-27824257BAE1

Q54483264-60A98075-5F41-413A-B765-1B1AFD1FE95F

Q54483264-6B5B4314-18B7-4069-8B0B-C3EB399C1533

P2860

Q54483264-03486F0A-F6F4-4BE9-9839-05A051063AF0

Q54483264-0722CD72-07C2-4EBE-A70B-3F3E667048B8

Q54483264-0DC581B8-47A8-41C6-88F7-38260E90948F

Q54483264-0E5FA686-F51E-4152-B383-BD4B59566F17

Q54483264-11CA7C9B-DC66-425F-98C3-903A57C1DF1F

Q54483264-1240833C-54D2-406F-B4BF-85AF89AEE86D

Q54483264-12D2DCFB-1B5C-4838-83E1-1B1742E69D1D

Q54483264-1C2BF168-CEBA-45CE-BCB2-D18E662EC362

Q54483264-1E27AF35-B503-4E6D-9AD6-295F92B8AF4E

Q54483264-233350CB-31E2-4D55-B94B-AB4D9BAE3ED6

P2888

Q54483264-AD893B38-9DB7-41F1-AEBB-0F9034AB041D

P304

Q54483264-C8FE5628-2309-4231-BA68-5BB083479BA6

P31

Q54483264-2CF9CA91-14A8-4BE7-9FFB-276825F3F79A

P356

Q54483264-D764A959-7B7F-433A-94BE-63EB648D53AC

P407

Q54483264-6C9E503B-F62A-4732-A738-33AD256E7770

P433

Q54483264-418E34C6-8D52-4B15-A6B0-FF0442A126C4

P478

Q54483264-3DDFEAD8-6FF5-47B3-87D0-DB74429BC52B

P50

Q54483264-2C1FCE21-48D2-41FF-A071-FE3CFC9A4D16

Q54483264-36D753B9-8A4E-4BE9-B3A8-EA73501EFBFA

Q54483264-E3916F53-6306-4BE6-AF6F-A175ADCF7D4D

P577

Q54483264-8D1A7E11-7281-47D1-B8E4-116540C53A69

P5875

Q54483264-049FFD79-B09F-45C6-B0FA-D4DB29C512B6

P698

Q54483264-51EC9253-2B8C-4D24-9ABA-B4D7007DE36C

P921

Q54483264-7C84D1B2-5D41-4B10-B508-17C9F1159485

P356

P1433

Nature Medicine

P1476

Endothelial PI3K-C2α, a class ...... and vascular barrier function

@en

P2093

Chisa Nagakura

http://www.w3.org/2001/XMLSchema#string

Hidekazu Miyazawa

http://www.w3.org/2001/XMLSchema#string

Hiroshi Okamoto

http://www.w3.org/2001/XMLSchema#string

Hong Cui

http://www.w3.org/2001/XMLSchema#string

Kazushi Sugihara

http://www.w3.org/2001/XMLSchema#string

Ken Asanuma

http://www.w3.org/2001/XMLSchema#string

Kotaro Yoshida

http://www.w3.org/2001/XMLSchema#string

Kuntal Biswas

http://www.w3.org/2001/XMLSchema#string

Masahide Asano

http://www.w3.org/2001/XMLSchema#string

Masaya Ueno

http://www.w3.org/2001/XMLSchema#string

P2860

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

Topographical expression of class IA and class II phosphoinositide 3-kinase enzymes in normal human tissues is consistent with a role in differentiation

Phosphoinositides in cell regulation and membrane dynamics

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

Critical role of the TIE2 endothelial cell receptor in the development of definitive hematopoiesis

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

Mechanisms of endocytosis

P2888

P304

1560-1569

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NM.2928

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P50

Takehiko Sasaki

P577

2012-09-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

230863985

http://www.w3.org/2001/XMLSchema#string

P698

22983395

http://www.w3.org/2001/XMLSchema#string

P921