The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
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The Dectin-2 family of C-type lectin-like receptors: an updateInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseSweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology.Liposomes as vaccine delivery systems: a review of the recent advances.The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signalingMincle-mediated translational regulation is required for strong nitric oxide production and inflammation resolution.Surfactin inducing mitochondria-dependent ROS to activate MAPKs, NF-κB and inflammasomes in macrophages for adjuvant activity.Association of C-Type Lectin Mincle with FcεRIβγ Subunits Leads to Functional Activation of RBL-2H3 Cells through Syk.Role of Fused Mycobacterium tuberculosis Immunogens and Adjuvants in Modern Tuberculosis Vaccines.Carbohydrate-based vaccine adjuvants - discovery and development.Human Mincle Binds to Cholesterol Crystals and Triggers Innate Immune Responses.C-type lectin receptors in the control of T helper cell differentiation.C-type lectin receptors in tuberculosis: what we know.Contact, Collaboration, and Conflict: Signal Integration of Syk-Coupled C-Type Lectin Receptors.Innate signaling by mycobacterial cell wall components and relevance for development of adjuvants for subunit vaccines.Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals.Stat6-Dependent Inhibition of Mincle Expression in Mouse and Human Antigen-Presenting Cells by the Th2 Cytokine IL-4IRAKM-Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease.The Mincle ligand trehalose dibehenate differentially modulates M1-like and M2-like macrophage phenotype and function via Syk signaling.The C-Type Lectin Mincle: Clues for a Role in Crohn's Disease Adjuvant Reaction.An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells.Strategies to Improve Vaccine Efficacy against Tuberculosis by Targeting Innate Immunity.Molecular and physiological roles of the adaptor protein CARD9 in immunity.PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection.Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation.
P2860
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P2860
The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-sg
2012年學術文章
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name
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@en
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@nl
type
label
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@en
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@nl
prefLabel
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@en
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@nl
P2093
P921
P1433
P1476
The mycobacterial cord factor ...... ivates the Nlrp3 inflammasome.
@en
P2093
Christian Peschel
Hendrik Poeck
Jürgen Ruland
Katrin Schweneker
Marc Schweneker
Olaf Gross
Oliver Gorka
P304
P356
10.1016/J.IMBIO.2012.07.029
P50
P577
2012-08-07T00:00:00Z