Increased interaction between PACT molecules in response to stress signals is required for PKR activation.

Increased interaction between PACT molecules in response to stress signals is required for PKR activation.

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http://www.wikidata.org/entity/Q54519466
PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expressiondsRNA binding protein PACT/RAX in gene silencing, development and diseases.Altered activation of protein kinase PKR and enhanced apoptosis in dystonia cells carrying a mutation in PKR activator protein PACT.Recent advances in the molecular pathogenesis of dystonia-plus syndromes and heredodegenerative dystonias.ADAR1 and PACT contribute to efficient translation of transcripts containing HIV-1 trans-activating response (TAR) element.Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs.S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells.The PKR activator, PACT, becomes a PKR inhibitor during HIV-1 replication.Clinical and therapeutic potential of protein kinase PKR in cancer and metabolism.The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation.DYT16 revisited: exome sequencing identifies PRKRA mutations in a European dystonia family.Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.Contribution of the two dsRBM motifs to the double-stranded RNA binding and protein interactions of PACT.Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival.Antipsychotic drug-associated gene-miRNA interaction in T-lymphocytes.
P2860

Increased interaction between PACT molecules in response to stress signals is required for PKR activation.

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http://www.wikidata.org/entity/Q54519466
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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Increased interaction between ...... s required for PKR activation.
@en
Increased interaction between ...... s required for PKR activation.
@nl
type
label
Increased interaction between ...... s required for PKR activation.
@en
Increased interaction between ...... s required for PKR activation.
@nl
prefLabel
Increased interaction between ...... s required for PKR activation.
@en
Increased interaction between ...... s required for PKR activation.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Increased interaction between ...... s required for PKR activation.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698