Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane.
about
Prohibitins role in cellular survival through Ras-Raf-MEK-ERK pathwayCharacterization of PHB1 and its role in mitochondrial maturation and yolk platelet degradation during development of Artemia embryosMultifaceted role of prohibitin in cell survival and apoptosisA novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulationRecombinant viral capsid protein VP1 suppresses lung cancer metastasis by inhibiting COX-2/PGE2 and MIG-7.MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis.Prohibitin: A Novel Molecular Player in KDEL Receptor Signalling.Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration.A Novel Class of Small Molecule Compounds that Inhibit Hepatitis C Virus Infection by Targeting the Prohibitin-CRaf Pathway.Comparative Proteomic Analysis of Advanced Ovarian Cancer Tissue to Identify Potential Biomarkers of Responders and Nonresponders to First-Line Chemotherapy of Carboplatin and Paclitaxel.Prohibitin overexpression predicts poor prognosis and promotes cell proliferation and invasion through ERK pathway activation in gallbladder cancer.Prohibitin-2 binding modulates insulin-like growth factor-binding protein-6 (IGFBP-6)-induced rhabdomyosarcoma cell migration.Prohibitin regulates the FSH signaling pathway in rat granulosa cell differentiation.Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progressionThe role of lipid raft translocation of prohibitin in regulation of Akt and Raf-protected apoptosis of HaCaT cells upon ultraviolet B irradiation.Extract of Perilla frutescens inhibits tumor proliferation of HCC via PI3K/AKT signal pathway.Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours.Prohibitin confers cytoprotection against ISO-induced hypertrophy in H9c2 cells via attenuation of oxidative stress and modulation of Akt/Gsk-3β signaling.Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting.A role for prohibitin in mast cell activation: location matters.The prohibitin protein complex promotes mitochondrial stabilization and cell survival in hematologic malignanciesProhibitin, relocated to the front ends, can control the migration directionality of colorectal cancer cells.Prohibitin Signaling at the Kidney Filtration Barrier.Proteomic analysis of mitochondria: biological and clinical progresses in cancer.Significance of prohibitin domain family in tumorigenesis and its implication in cancer diagnosis and treatment.Targeting prohibitins at the cell surface prevents Th17-mediated autoimmunity
P2860
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P2860
Raf activation by Ras and promotion of cellular metastasis require phosphorylation of prohibitin in the raft domain of the plasma membrane.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Raf activation by Ras and prom ...... domain of the plasma membrane.
@en
Raf activation by Ras and prom ...... domain of the plasma membrane.
@nl
type
label
Raf activation by Ras and prom ...... domain of the plasma membrane.
@en
Raf activation by Ras and prom ...... domain of the plasma membrane.
@nl
prefLabel
Raf activation by Ras and prom ...... domain of the plasma membrane.
@en
Raf activation by Ras and prom ...... domain of the plasma membrane.
@nl
P2093
P2860
P356
P1433
P1476
Raf activation by Ras and prom ...... domain of the plasma membrane
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.86
P407
P577
2012-03-12T00:00:00Z