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Mutation of the PDK1 PH Domain Inhibits Protein Kinase B/Akt, Leading to Small Size and Insulin ResistanceInvestigation of salicylate hepatic responses in comparison with chemical analogues of the drugMouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour.Cellular responses to the metal-binding properties of metformin.Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin.Genetic variants in human sterol regulatory element binding protein-1c in syndromes of severe insulin resistance and type 2 diabetes.Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells.Metformin selectively targets redox control of complex I energy transduction.Insulin resistance in polycystic ovary syndrome is associated with defective regulation of ERK1/2 by insulin in skeletal muscle in vivo.Generation, validation and humanisation of a novel insulin resistant cell model.Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).The anti-neurodegenerative agent clioquinol regulates the transcription factor FOXO1a.Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
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հետազոտող
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name
Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
@nl
Lisa Logie
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type
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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Lisa Logie
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P106
P1153
20734508200
P21
P31
P496
0000-0003-4955-7427