Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites.
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Precursor peptide progastrin(1-80) reduces apoptosis of intestinal epithelial cells and upregulates cytochrome c oxidase Vb levels and synthesis of ATPProgastrin Peptides Increase the Risk of Developing Colonic Tumors: Impact on Colonic Stem CellsAnnexin II binds progastrin and gastrin-like peptides, and mediates growth factor effects of autocrine and exogenous gastrins on colon cancer and intestinal epithelial cells.Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure.Activation of pro-oncogenic pathways in colorectal hyperplastic polyps.Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E2 productionClathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2.Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: phenotypic differences between transformed and nontransformed stem cells.Role of gastrin-peptides in Barrett's and colorectal carcinogenesis.Achlorhydria is associated with gastric microbial overgrowth and development of cancer: lessons learned from the gastrin knockout mouse.P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in micePeptide processing and biology in human disease.Biologically active, non membrane-anchored precursors: an overview.Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.Functional cross-talk between beta-catenin and NFkappaB signaling pathways in colonic crypts of mice in response to progastrin.Flow cytometric detection of progastrin interaction with gastrointestinal cells.The G-protein coupled receptor 56, expressed in colonic stem and cancer cells, binds progastrin to promote proliferation and carcinogenesis.Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo.Targeting progastrin enhances radiosensitization of colorectal cancer cells.Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice.A gastrin precursor, gastrin-gly, upregulates VEGF expression in colonic epithelial cells through an HIF-1-independent mechanism.Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.Mineralocorticoids act centrally to regulate blood-borne tumor necrosis factor-alpha in normal rats.Acute myocardial infarction induces hypothalamic cytokine synthesis.Neural regulation of the proinflammatory cytokine response to acute myocardial infarction.Brain angiotensin-converting enzyme activity and autonomic regulation in heart failure.Significant increase in the aggressive behavior of transgenic mice overexpressing peripheral progastrin peptides: associated changes in CCK2 and serotonin receptors in the CNS.
P2860
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P2860
Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
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name
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@en
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@nl
type
label
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@en
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@nl
prefLabel
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@en
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@nl
P2093
P2860
P356
P1476
Progastrin1-80 stimulates grow ...... a high-affinity binding sites.
@en
P2093
Tarasova N
P2860
P304
P356
10.1152/AJPGI.00351.2002
P577
2002-10-16T00:00:00Z