TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.
about
15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancersHLTF gene silencing in human colon cancer.The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancersTransforming growth factor-beta and breast cancer: Tumor promoting effects of transforming growth factor-betaA benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor geneNative and activated forms of alpha 2-macroglobulin increase expression of platelet-derived growth factor alpha-receptor in vascular smooth muscle cells. Evidence for autocrine transforming growth factor-beta activity.Murine alpha-macroglobulins demonstrate divergent activities as neutralizers of transforming growth factor-beta and as inducers of nitric oxide synthesis. A possible mechanism for the endotoxin insensitivity of the alpha2-macroglobulin gene knock-ouDEC1 is a downstream target of TGF-beta with sequence-specific transcriptional repressor activities.Angiogenesis in breast cancer: the role of transforming growth factor beta and CD105.TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis.The timing of TGF-β inhibition affects the generation of antigen-specific CD8+ T cellsRestoration of transforming growth factor-beta receptor II expression in colon cancer cells with microsatellite instability increases metastatic potential in vivo.Overexpression of the dynein light chain km23-1 in human ovarian carcinoma cells inhibits tumor formation in vivo and causes mitotic delay at prometaphase/metaphase.Knockdown of c-Fos suppresses the growth of human colon carcinoma cells in athymic mice.Transforming growth factor-beta: recent progress and new challenges.Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.Proliferation of mutators in A cell population.Identification of novel and differentially expressed MicroRNAs in goat enzootic nasal adenocarcinomaInterleukin-6 undergoes transition from paracrine growth inhibitor to autocrine stimulator during human melanoma progression.Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion.Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells.TGF beta1 and related-Smads contribute to pulmonary metastasis of hepatocellular carcinoma in mice model.Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration.Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.Enhanced translational efficiency of a novel transforming growth factor beta 3 mRNA in human breast cancer cells.MicroRNA-mRNA interactions in colorectal cancer and their role in tumor progression.TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology.The Effects of miR-20a on p21: Two Mechanisms Blocking Growth Arrest in TGF-β-Responsive Colon Carcinoma.GFAP promoter-driven RNA interference on TGF-β1 to treat liver fibrosis.Phosphatase PRL-3 is a direct regulatory target of TGFbeta in colon cancer metastasis.A dominant inhibitory mutant of the type II transforming growth factor beta receptor in the malignant progression of a cutaneous T-cell lymphomaDysregulation of autocrine TGF-beta isoform production and ligand responses in human tumour-derived and Ha-ras-transfected keratinocytes and fibroblasts.Transforming growth factor beta-1 in rectal tumour, mucosa and plasma in relation to radiotherapy and clinical outcome in rectal cancer patients.Activation of the TGFalpha autocrine loop is downstream of IGF-I receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells.Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells.Role of transforming growth factor beta in colorectal cancer.Multiple autocrine factors including an extracellular matrix protein are required for the proliferation and spreading of human colon carcinoma cells in vitro.Characterization of a newly established human pancreatic carcinoma cell line, UK Pan-1.Efficacy and specificity of antisense laminin chain-specific expression vectors in blocking laminin induction by TGFbeta1: effect of laminin blockade on TGFbeta1-mediated cellular responses.
P2860
Q24318523-1F05FD71-828F-4233-8FD5-B846825D439FQ24536137-A4C491B6-BEAE-4F71-A038-651497F12415Q24658079-7E060147-CBB8-4BC4-ADF2-FCEA0D621387Q24793319-A13C12C0-AE57-42A0-9DFA-ED5BE6B6DD84Q30449276-EC680C54-6ABD-466B-AE5C-2C4EA07FF3DCQ30467899-FB112D00-B22F-4028-B209-4825106CF2A1Q30469104-35F7ECC7-7C8D-44B3-BB9F-036FE9386720Q34014701-33A9E385-C063-4790-B13D-DCB76D259CEDQ34136521-D4521F89-FACA-4FA2-A9FE-F05F74CC6C92Q34639841-35B6E60B-2E74-469E-B1FC-D3C16334F81DQ34832951-7F651C53-2642-4042-98AF-8116240A9264Q34963434-22613779-2060-4D74-99DE-1B405C0DF5DBQ35011977-042630E5-E1E5-4EE3-AF72-397B0E42EB0CQ35184753-FF35706C-AC37-4E72-AC4E-EA3A05F6DD7AQ35236115-E7DFE16A-274E-4628-9B6C-03E4DAEFE5A7Q35544657-20B18F87-D9E7-48CE-8515-9E93F77BC937Q35618973-5C25B88B-17AE-47BA-88C8-26ACE07AE991Q36185927-7B0A878A-E69B-4A2D-A3D9-8FEA9499789EQ36233022-CB80A71B-68BE-4C97-9723-19E8386CBC90Q36392971-9541B722-395F-4D7B-B986-2B2CAA7795ABQ36401309-2623675F-9DD2-446B-875D-4C1D00E14A1DQ36416504-79FE04C7-F507-440E-9BE7-3764545D0ED6Q36483438-0C4B9C92-F9DA-4FDC-A92E-FC98EE6168D5Q36531643-21AAF7F8-215B-4D96-A0A7-C60E5E5239D1Q36544364-D885F2FF-7889-4CA1-A5EB-FE5CF723B3F6Q36644133-68D4168F-F535-4AB5-B56C-BEFFB52EBD07Q38331867-42B15F91-AC3C-46C6-9A65-A9F4C06F3596Q38824306-6938BFA6-602E-4AD9-A055-3C98273D543FQ38870781-85C8AB5B-D243-4767-BDD1-658A31E4D9B1Q39586742-8B620A8E-0A80-47C8-BF30-1E6E94DAC285Q39630626-28AE999B-B2F6-4586-A81F-1A0F67D16ECFQ40019241-21341ADE-9F82-463A-BA5F-1F3D91C059A3Q40069672-8891F2A3-EF46-4F85-9680-DBF9984DFE3AQ40189889-1D8AB86C-A35F-4E6F-B7C0-10F01F4B4FD0Q40735877-232F020D-B5C4-4BB4-8649-DCB7D7A25C02Q40789892-12A151AA-16D7-420D-801F-EA3F541FBF54Q40856616-2604529A-22AD-4403-A490-0E7F08E08E80Q40876989-7A61C99D-0692-42C3-95A9-98B4D6F6D92AQ40879460-682C4301-382E-4A1A-8D80-388F97E29361Q40973299-4AA50C61-951E-475F-BD02-171AEF30908F
P2860
TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@ast
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@en
type
label
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@ast
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@en
prefLabel
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@ast
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@en
P2093
P2860
P356
P1476
TGF-beta 1 is an autocrine-neg ...... n antisense expression vector.
@en
P2093
D Theodorescu
J K Willson
K M Mulder
L E Humphrey
M G Brattain
R S Kerbel
P2860
P304
P356
10.1083/JCB.116.1.187
P407
P577
1992-01-01T00:00:00Z